C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: DENN/MADD domain containing 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000036661 Dennd3 10090 + 15:73512560-73572242 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000043414 Dennd3-001 73512560-73572242 protein_coding
  ENSMUST00000159322 Dennd3-006 73564862-73567077 retained_intron
  ENSMUST00000160267 Dennd3-003 73557636-73568107 nonsense_mediated_decay
  ENSMUST00000160727 Dennd3-007 73567078-73570899 retained_intron
  ENSMUST00000162488 Dennd3-002 73522342-73570954 protein_coding
  ENSMUST00000162824 Dennd3-005 73518614-73523545 processed_transcript
  ENSMUST00000173292 Dennd3-008 73512672-73572099 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000043414ENSMUST00000160727ENSMUST00000162488ENSMUST00000173292
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000043414 3.572±0.64 2.013±0.52 2.870±0.04 0.404±0.00 4.440±1.23 4.048±0.60 2.375±0.89 8.873±1.22 0.833±0.35 26.286±3.92 0.650±0.29 3.633±0.87 0.955±0.62 0.487±0.14
ENSMUST00000160727 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.603±0.00 N/A
ENSMUST00000162488 N/A N/A N/A N/A N/A N/A 0.653±0.00 N/A N/A N/A N/A 0.985±0.20 N/A 0.526±0.00
ENSMUST00000173292 N/A N/A N/A 0.400±0.19 N/A N/A N/A 1.682±0.13 0.211±0.11 N/A 0.295±0.00 0.919±0.00 0.399±0.21 0.777±0.38

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006FQ CIL_0006FQ_0003 CGP 15:73205105-73572242
CIL_0007WG CIL_0007WG_0002 VISTA 15:73439611-74047146
CIL_0000X9 CIL_0000X9_0003 CGP 15:73512560-73645762

Gene Ontology
GO IDEvidence TypeGO Description
GO:0008333 IGI endosome to lysosome transport
GO:0017112 IGI Rab guanyl-nucleotide exchange factor activity
GO:0032851 IGI positive regulation of Rab GTPase activity
GO:0044257 IMP cellular protein catabolic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000013153 dennd3b DENN/MADD domain containing 3b protein_coding Danio_rerio
ENSDARG00000078797 dennd3a DENN/MADD domain containing 3a protein_coding Danio_rerio
ENSG00000105339 DENND3 DENN/MADD domain containing 3 protein_coding Homo_sapiens

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