C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: histocompatibility 2, class II, locus Mb2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000037548 H2-DMb2 10090 + 17:34143307-34151553 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000041982 H2-DMb2-001 34145313-34151553 protein_coding
  ENSMUST00000171231 H2-DMb2-002 34145271-34151549 protein_coding
  ENSMUST00000173262 H2-DMb2-003 34143307-34147839 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000041982ENSMUST00000171231ENSMUST00000173262
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000041982 1.767±0.53 0.715±0.34 2.152±0.25 0.231±0.02 35.473±16.36 5.210±0.88 0.800±0.62 2.403±1.44 0.455±0.21 9.347±2.61 0.916±1.64 1.205±0.69 0.288±0.26 0.120±0.05
ENSMUST00000171231 0.379±0.09 0.452±0.14 0.364±0.00 N/A 6.751±2.01 2.498±0.56 0.612±0.33 1.086±0.57 0.305±0.18 3.977±0.00 0.148±0.07 0.837±0.41 N/A N/A
ENSMUST00000173262 N/A N/A N/A 0.320±0.00 N/A N/A N/A N/A 0.302±0.00 N/A N/A 0.334±0.00 N/A 0.140±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001PK CIL_0001PK_0005 CGP 17:34143307-34160230

Gene Ontology

GO IDEvidence TypeGO Description
GO:0002474 IEA antigen processing and presentation of peptide antigen via MHC class I
GO:0005515 IPI protein binding
GO:0005764 IDA lysosome
GO:0005765 IDA lysosomal membrane
GO:0005770 IDA late endosome
GO:0005771 IDA multivesicular body
GO:0006955 IEA immune response
GO:0010008 IDA endosome membrane
GO:0016021 IDA integral component of membrane
GO:0019882 IDA antigen processing and presentation
GO:0019886 IDA antigen processing and presentation of exogenous peptide antigen via MHC class II
GO:0042612 IEA MHC class I protein complex
GO:0042613 IEA MHC class II protein complex
GO:0051085 IDA chaperone mediated protein folding requiring cofactor

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000041705 si:busm1-228j01.6 si:busm1-228j01.6 protein_coding Danio_rerio
ENSDARG00000053738 si:dkey-33b17.3 si:dkey-33b17.3 protein_coding Danio_rerio
ENSDARG00000054921 wu:fd58b11 wu:fd58b11 protein_coding Danio_rerio
ENSDARG00000055447 si:busm1-194e12.12 si:busm1-194e12.12 protein_coding Danio_rerio
ENSDARG00000056330 mhc2dbb major histocompatibility complex class II DBB gene protein_coding Danio_rerio
ENSDARG00000074510 si:busm1-104n07.3 si:busm1-104n07.3 protein_coding Danio_rerio
ENSDARG00000076307 si:zfos-2070c2.3 si:zfos-2070c2.3 protein_coding Danio_rerio
ENSDARG00000079105 mhc2dab major histocompatibility complex class II DAB gene protein_coding Danio_rerio
ENSDARG00000088872 si:busm1-228j01.4 si:busm1-228j01.4 protein_coding Danio_rerio
ENSDARG00000093706 si:dkey-33b17.3 si:dkey-33b17.3 protein_coding Danio_rerio
ENSG00000242574 HLA-DMB major histocompatibility complex, class II, DM beta protein_coding Homo_sapiens
ENSG00000248993 XXbac-BPG181M17.5 Uncharacterized protein {ECO:0000313|Ensembl:ENSP00000412457} protein_coding Homo_sapiens

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