C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: protein kinase C, iota
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000108249 Prkci-001 ENSMUSG00000037643 10090 + 3:30995747-31052741 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000108249
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000108249 12.595±2.01 4.557±0.86 32.160±5.81 11.031±2.70 9.730±1.08 14.838±6.11 3.026±0.35 8.307±0.52 4.045±1.39 25.402±4.68 0.768±0.26 6.958±2.50 15.830±8.00 3.595±1.60

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002XN CIL_0002XN_0002 CGP 3:30899295-31052741
CIL_0002XK CIL_0002XK_0002 CGP 3:30995747-31122577

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000139 IEA Golgi membrane
GO:0004672 ISS protein kinase activity
GO:0004674 ISS protein serine/threonine kinase activity
GO:0004697 IDA protein kinase C activity
GO:0005543 ISS phospholipid binding
GO:0005634 IDA:ISS nucleus
GO:0005737 IDA cytoplasm
GO:0005768 IEA endosome
GO:0005829 ISS cytosol
GO:0005886 IEA plasma membrane
GO:0005923 IEA tight junction
GO:0006468 IDA protein phosphorylation
GO:0007015 IMP actin filament organization
GO:0008270 IEA zinc ion binding
GO:0010976 ISS positive regulation of neuron projection development
GO:0015630 IEA microtubule cytoskeleton
GO:0016324 IDA apical plasma membrane
GO:0016477 IEA cell migration
GO:0019904 IEA protein domain specific binding
GO:0031252 IEA cell leading edge
GO:0032869 IMP cellular response to insulin stimulus
GO:0034351 ISS negative regulation of glial cell apoptotic process
GO:0034613 IEA cellular protein localization
GO:0035089 IMP establishment of apical/basal cell polarity
GO:0035556 IEA intracellular signal transduction
GO:0042462 IMP eye photoreceptor cell development
GO:0043220 IDA Schmidt-Lanterman incisure
GO:0043234 IEA protein complex
GO:0043434 IEA response to peptide hormone
GO:0043524 ISS negative regulation of neuron apoptotic process
GO:0045171 IEA intercellular bridge
GO:0045177 IDA apical part of cell
GO:0045216 ISS cell-cell junction organization
GO:0046326 IMP positive regulation of glucose import
GO:0048194 IEA Golgi vesicle budding
GO:0051092 ISS positive regulation of NF-kappaB transcription factor activity
GO:0060252 ISS positive regulation of glial cell proliferation
GO:0070062 IEA extracellular vesicular exosome
GO:0070555 IEA response to interleukin-1
GO:0090004 IMP positive regulation of establishment of protein localization to plasma membrane
GO:2000353 ISS positive regulation of endothelial cell apoptotic process

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000295797 PRKCI-001 protein_coding Homo_sapiens 0 2464
ENST00000392722 RP3-514P16.1-001 processed_pseudogene Homo_sapiens 0 2093
ENST00000476635 PRKCI-002 retained_intron Homo_sapiens 0 789
ENST00000482353 PRKCI-005 retained_intron Homo_sapiens 0 322
ENST00000485837 PRKCI-007 retained_intron Homo_sapiens 0 673
ENST00000488541 PRKCI-004 retained_intron Homo_sapiens 0 327
ENST00000493761 PRKCI-003 retained_intron Homo_sapiens 0 344

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