C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: cyclin-dependent kinase inhibitor 1C (P57)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000037664 Cdkn1c 10090 - 7:143458350-143461050 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000037287 Cdkn1c-201 143458350-143461050 protein_coding
  ENSMUST00000167912 Cdkn1c-202 143458350-143461050 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000037287ENSMUST00000167912
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000037287 5.894±1.47 180.012±30.48 3.973±0.87 33.206±16.64 7.514±2.23 3.471±0.71 2.503±0.51 6.021±2.64 24.390±24.63 5.864±0.57 4.704±0.75 5.561±2.11 415.908±208.45 2.107±0.33
ENSMUST00000167912 4.365±1.22 50.719±7.54 1.254±0.31 12.834±3.76 6.491±1.84 2.306±1.06 1.579±0.60 5.388±1.06 4.690±4.64 3.811±1.05 1.426±0.32 4.243±1.17 153.407±87.76 3.036±1.59

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008A3 CIL_0008A3_0002 VISTA 7:142895498-143499796
CIL_0003FM CIL_0003FM_0003 CGP 7:143106362-143461050

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IGI negative regulation of transcription from RNA polymerase II promoter
GO:0001501 IMP skeletal system development
GO:0001822 IMP kidney development
GO:0001890 IMP placenta development
GO:0004861 IEA cyclin-dependent protein serine/threonine kinase inhibitor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IEA cytoplasm
GO:0007050 IEA cell cycle arrest
GO:0007568 IMP aging
GO:0030099 IGI myeloid cell differentiation
GO:0030325 IMP adrenal gland development
GO:0030511 IEA positive regulation of transforming growth factor beta receptor signaling pathway
GO:0033673 IEA negative regulation of kinase activity
GO:0035264 IMP multicellular organism growth
GO:0042326 IDA negative regulation of phosphorylation
GO:0042551 IMP neuron maturation
GO:0043010 IMP camera-type eye development
GO:0045892 IEA negative regulation of transcription, DNA-templated
GO:0045893 IEA positive regulation of transcription, DNA-templated
GO:0050680 IEA negative regulation of epithelial cell proliferation
GO:0055123 IMP digestive system development
GO:0060065 IMP uterus development
GO:0060669 IMP embryonic placenta morphogenesis
GO:0071514 IMP genetic imprinting
GO:0071901 IEA negative regulation of protein serine/threonine kinase activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000010878 cdkn1c cyclin-dependent kinase inhibitor 1C protein_coding Danio_rerio
ENSDARG00000089854 CDKN1C (2 of 2) cyclin-dependent kinase inhibitor 1C (p57, Kip2) protein_coding Danio_rerio
ENSG00000129757 CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2) protein_coding Homo_sapiens

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