C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: solute carrier family 24 (sodium/potassium/calcium exchanger), member 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000037996 Slc24a2 10090 - 4:86983124-87230477 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000044990 Slc24a2-005 86991173-87227873 protein_coding
  ENSMUST00000107155 Slc24a2-006 86991173-87227877 protein_coding
  ENSMUST00000107157 Slc24a2-001 86983124-87230477 protein_coding
  ENSMUST00000107158 Slc24a2-201 86983129-87227963 protein_coding
  ENSMUST00000134248 Slc24a2-003 87072442-87230423 processed_transcript
  ENSMUST00000134643 Slc24a2-004 87072830-87230422 processed_transcript
  ENSMUST00000140780 Slc24a2-008 86996136-87011673 processed_transcript
  ENSMUST00000146815 Slc24a2-007 87028283-87176285 protein_coding
  ENSMUST00000155361 Slc24a2-002 87175785-87230467 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000044990ENSMUST00000107155ENSMUST00000107157ENSMUST00000107158ENSMUST00000134643ENSMUST00000146815ENSMUST00000155361
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000044990 N/A N/A N/A N/A N/A 0.084±0.03 0.204±0.00 0.011±0.00 N/A 0.115±0.00 N/A 0.119±0.07 N/A N/A
ENSMUST00000107155 N/A N/A N/A N/A N/A N/A 0.204±0.05 0.011±0.00 0.012±0.01 N/A N/A N/A N/A 0.204±0.00
ENSMUST00000107157 0.018±0.01 0.377±0.16 N/A 0.418±0.05 0.008±0.00 N/A 0.169±0.05 0.008±0.00 0.002±0.00 0.057±0.02 0.078±0.03 0.037±0.03 0.001±0.00 0.057±0.05
ENSMUST00000107158 0.014±0.00 N/A 0.009±0.00 9.049±0.00 0.014±0.01 0.027±0.01 N/A N/A 0.002±0.00 N/A 0.086±0.00 0.042±0.02 0.002±0.00 N/A
ENSMUST00000134643 N/A N/A N/A N/A 0.053±0.02 N/A N/A 0.027±0.02 0.021±0.00 0.063±0.02 N/A 0.073±0.00 N/A 0.161±0.00
ENSMUST00000146815 N/A N/A N/A N/A N/A N/A N/A N/A 0.050±0.00 N/A N/A 0.263±0.00 N/A 0.163±0.00
ENSMUST00000155361 0.022±0.00 N/A N/A N/A 0.059±0.00 N/A N/A 0.017±0.00 0.010±0.00 0.110±0.00 N/A 0.137±0.10 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007DB CIL_0007DB_0002 CGP 4:86874396-87230477
CIL_0007D2 CIL_0007D2_0002 CGP 4:86983124-88033364

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005262 IDA calcium channel activity
GO:0005509 IEA calcium ion binding
GO:0006816 IDA calcium ion transport
GO:0006874 IMP cellular calcium ion homeostasis
GO:0007612 IMP learning
GO:0007613 IMP memory
GO:0008273 ISO calcium, potassium:sodium antiporter activity
GO:0016020 IDA membrane
GO:0016021 IEA integral component of membrane
GO:0016151 IEA nickel cation binding
GO:0030145 IEA manganese ion binding
GO:0030955 IEA potassium ion binding
GO:0031226 IEA intrinsic component of plasma membrane
GO:0031402 IEA sodium ion binding
GO:0034220 ISO ion transmembrane transport
GO:0035725 ISO sodium ion transmembrane transport
GO:0046870 IEA cadmium ion binding
GO:0046983 IEA protein dimerization activity
GO:0060291 IMP long-term synaptic potentiation
GO:0060292 IMP long term synaptic depression
GO:0070588 IDA calcium ion transmembrane transport

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000042988 SLC24A2 (1 of 2) solute carrier family 24 (sodium/potassium/calcium exchanger), member 2 protein_coding Danio_rerio
ENSDARG00000063158 SLC24A2 (2 of 2) solute carrier family 24 (sodium/potassium/calcium exchanger), member 2 protein_coding Danio_rerio
ENSG00000155886 SLC24A2 solute carrier family 24 (sodium/potassium/calcium exchanger), member 2 protein_coding Homo_sapiens

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