C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: alkaline ceramidase 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000038007 Acer2 10090 + 4:86874396-86934822 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000045224 Acer2-001 86874396-86920875 protein_coding
  ENSMUST00000084433 Acer2-002 86874414-86920875 protein_coding
  ENSMUST00000128712 Acer2-003 86874414-86932491 processed_transcript
  ENSMUST00000135874 Acer2-004 86930691-86934822 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000045224ENSMUST00000084433ENSMUST00000128712ENSMUST00000135874
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000045224 9.431±4.56 7.532±0.63 141.880±35.94 0.688±0.13 7.305±1.05 2.630±0.53 7.189±0.33 9.307±0.82 3.551±2.46 91.123±26.24 0.590±0.30 2.149±0.71 12.172±12.71 1.453±0.08
ENSMUST00000084433 N/A 1.178±0.00 N/A 0.713±0.00 N/A N/A N/A N/A 0.509±0.00 N/A 0.578±0.32 0.505±0.00 1.684±0.11 0.205±0.00
ENSMUST00000128712 3.461±0.12 6.187±1.90 N/A 2.128±0.97 4.276±1.12 1.790±0.47 4.811±0.00 6.017±0.85 1.501±0.14 82.369±37.97 0.369±0.01 2.013±0.69 17.284±14.19 3.843±0.64
ENSMUST00000135874 N/A N/A N/A 1.745±0.26 N/A 0.734±0.11 N/A N/A 0.485±0.00 N/A N/A 0.114±0.00 1.167±0.22 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007DC CIL_0007DC_0002 CGP 4:86854660-86934822
CIL_0007DB CIL_0007DB_0002 CGP 4:86874396-87230477

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001953 IEA negative regulation of cell-matrix adhesion
GO:0005794 IEA Golgi apparatus
GO:0006672 IEA ceramide metabolic process
GO:0006919 IEA activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0008284 IEA positive regulation of cell proliferation
GO:0010942 IEA positive regulation of cell death
GO:0017040 IEA ceramidase activity
GO:0030173 IEA integral component of Golgi membrane
GO:0032526 IEA response to retinoic acid
GO:0033629 IEA negative regulation of cell adhesion mediated by integrin
GO:0035690 IEA cellular response to drug
GO:0046512 IEA sphingosine biosynthetic process
GO:0071633 IEA dihydroceramidase activity
GO:0090285 IEA negative regulation of protein glycosylation in Golgi

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000077782 ACER2 alkaline ceramidase 2 protein_coding Danio_rerio
ENSG00000177076 ACER2 alkaline ceramidase 2 protein_coding Homo_sapiens

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