C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: pyruvate dehydrogenase kinase, isoenzyme 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000038967 Pdk2 10090 - 11:95026258-95041354 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000038431 Pdk2-001 95026258-95041354 protein_coding
  ENSMUST00000126730 Pdk2-005 95026954-95028576 processed_transcript
  ENSMUST00000129262 Pdk2-004 95028728-95029424 processed_transcript
  ENSMUST00000141712 Pdk2-003 95029654-95040558 processed_transcript
  ENSMUST00000155857 Pdk2-002 95031914-95040875 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000038431ENSMUST00000126730
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000038431 33.770±7.04 48.768±4.10 20.688±4.58 10.758±5.26 57.135±25.03 30.710±0.73 165.871±36.44 154.131±4.70 25.478±21.48 23.279±0.19 179.502±6.03 24.395±5.61 3.751±2.52 78.181±31.42
ENSMUST00000126730 N/A N/A N/A 40.632±0.00 N/A N/A N/A N/A N/A N/A N/A 15.878±0.00 12.545±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00088W CIL_00088W_0002 VISTA 11:94580928-95183811

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004674 IEA protein serine/threonine kinase activity
GO:0004740 IMP pyruvate dehydrogenase (acetyl-transferring) kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005739 IDA mitochondrion
GO:0005967 IDA mitochondrial pyruvate dehydrogenase complex
GO:0006006 IEA glucose metabolic process
GO:0006111 IMP regulation of gluconeogenesis
GO:0006468 IEA protein phosphorylation
GO:0006885 IMP regulation of pH
GO:0008286 IMP insulin receptor signaling pathway
GO:0010510 IMP regulation of acetyl-CoA biosynthetic process from pyruvate
GO:0010565 IMP regulation of cellular ketone metabolic process
GO:0010906 IMP regulation of glucose metabolic process
GO:0031670 IMP cellular response to nutrient
GO:0034614 IEA cellular response to reactive oxygen species
GO:0042593 IMP glucose homeostasis
GO:0042803 IEA protein homodimerization activity
GO:0072332 IEA intrinsic apoptotic signaling pathway by p53 class mediator

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000020876 PDK2 (1 of 2) pyruvate dehydrogenase kinase, isozyme 2 protein_coding Danio_rerio
ENSDARG00000059054 pdk2 pyruvate dehydrogenase kinase, isoenzyme 2 protein_coding Danio_rerio
ENSG00000005882 PDK2 pyruvate dehydrogenase kinase, isozyme 2 protein_coding Homo_sapiens

Loading