C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: pyruvate dehydrogenase kinase, isoenzyme 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000038431 Pdk2-001 ENSMUSG00000038967 10090 - 11:95026258-95041354 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000038431
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000038431 33.770±7.04 48.768±4.10 20.688±4.58 10.758±5.26 57.135±25.03 30.710±0.73 165.871±36.44 154.131±4.70 25.478±21.48 23.279±0.19 179.502±6.03 24.395±5.61 3.751±2.52 78.181±31.42

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00088W CIL_00088W_0002 VISTA 11:94580928-95183811

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004674 IEA protein serine/threonine kinase activity
GO:0004740 IMP pyruvate dehydrogenase (acetyl-transferring) kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005739 IDA mitochondrion
GO:0005967 IDA mitochondrial pyruvate dehydrogenase complex
GO:0006006 IEA glucose metabolic process
GO:0006111 IMP regulation of gluconeogenesis
GO:0006468 IEA protein phosphorylation
GO:0006885 IMP regulation of pH
GO:0008286 IMP insulin receptor signaling pathway
GO:0010510 IMP regulation of acetyl-CoA biosynthetic process from pyruvate
GO:0010565 IMP regulation of cellular ketone metabolic process
GO:0010906 IMP regulation of glucose metabolic process
GO:0031670 IMP cellular response to nutrient
GO:0034614 IEA cellular response to reactive oxygen species
GO:0042593 IMP glucose homeostasis
GO:0042803 IEA protein homodimerization activity
GO:0072332 IEA intrinsic apoptotic signaling pathway by p53 class mediator

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000007708 PDK2-003 protein_coding Homo_sapiens 0 1546
ENST00000503076 PDK2-018 retained_intron Homo_sapiens 0 278
ENST00000503176 PDK2-001 protein_coding Homo_sapiens 0 1731
ENST00000503614 PDK2-009 protein_coding Homo_sapiens 0 1136
ENST00000505440 PDK2-012 protein_coding Homo_sapiens 0 684
ENST00000505897 PDK2-011 retained_intron Homo_sapiens 0 736
ENST00000506242 PDK2-017 retained_intron Homo_sapiens 0 599
ENST00000506647 PDK2-020 retained_intron Homo_sapiens 0 466
ENST00000508030 PDK2-008 protein_coding Homo_sapiens 0 652
ENST00000508960 PDK2-010 retained_intron Homo_sapiens 0 381
ENST00000510219 PDK2-016 protein_coding Homo_sapiens 0 693
ENST00000512204 PDK2-019 retained_intron Homo_sapiens 0 734
ENST00000512238 PDK2-014 protein_coding Homo_sapiens 0 518
ENST00000515040 PDK2-015 retained_intron Homo_sapiens 0 752
ENST00000614357 PDK2-201 protein_coding Homo_sapiens 0 1544

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