C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: polymerase (DNA directed), gamma
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000039176 Polg 10090 - 7:79448791-79466362 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000073889 Polg-001 79448791-79466362 protein_coding
  ENSMUST00000125562 Polg-005 79464895-79466070 processed_transcript
  ENSMUST00000127082 Polg-003 79449382-79466187 retained_intron
  ENSMUST00000127734 Polg-011 79454532-79455394 retained_intron
  ENSMUST00000132048 Polg-009 79454135-79459297 processed_transcript
  ENSMUST00000139290 Polg-014 79449387-79450648 processed_transcript
  ENSMUST00000139597 Polg-010 79454038-79456065 retained_intron
  ENSMUST00000139668 Polg-008 79455486-79459302 protein_coding
  ENSMUST00000139795 Polg-012 79451930-79454340 retained_intron
  ENSMUST00000142915 Polg-006 79460270-79461903 retained_intron
  ENSMUST00000143672 Polg-007 79456070-79459794 protein_coding
  ENSMUST00000145154 Polg-013 79450169-79452080 retained_intron
  ENSMUST00000149444 Polg-002 79449563-79466180 nonsense_mediated_decay
  ENSMUST00000154403 Polg-004 79449382-79455080 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000073889ENSMUST00000127082ENSMUST00000139795ENSMUST00000149444ENSMUST00000154403
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000073889 4.662±1.25 5.366±1.65 5.068±0.86 4.960±0.27 8.007±4.03 9.082±3.38 3.683±0.70 4.546±1.16 4.639±1.90 7.128±3.30 1.318±0.31 13.490±5.45 13.577±4.11 4.591±0.33
ENSMUST00000127082 3.842±0.56 12.996±1.54 3.346±0.29 3.490±0.13 7.670±2.40 10.182±1.42 2.290±0.30 3.426±0.89 5.169±1.44 7.008±0.22 2.963±0.60 7.862±3.05 17.472±10.74 8.037±0.44
ENSMUST00000139795 N/A N/A N/A 27.167±0.00 N/A N/A N/A N/A N/A N/A N/A 27.497±0.00 N/A 54.652±0.00
ENSMUST00000149444 5.139±1.82 N/A 2.951±0.55 5.859±4.24 5.764±1.17 N/A 4.463±0.37 3.560±0.52 3.273±0.71 3.618±0.00 2.940±0.52 7.702±3.47 19.872±10.18 12.311±5.75
ENSMUST00000154403 6.733±0.81 N/A 5.148±0.68 N/A 6.081±0.35 8.448±0.00 3.479±0.00 3.996±0.00 N/A 9.203±0.00 N/A 8.752±2.24 31.971±17.15 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00011C CIL_00011C_0002 CGP 7:79374871-79450265
CIL_0002RC CIL_0002RC_0003 CGP 7:79391929-79466362
CIL_0002R9 CIL_0002R9_0003 CGP 7:79448791-79617657

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002020 IEA protease binding
GO:0003677 IEA DNA binding
GO:0003682 IEA chromatin binding
GO:0003887 ISO DNA-directed DNA polymerase activity
GO:0004527 IDA exonuclease activity
GO:0005515 IPI protein binding
GO:0005739 IDA mitochondrion
GO:0005743 IDA mitochondrial inner membrane
GO:0005760 IEA gamma DNA polymerase complex
GO:0006264 IMP mitochondrial DNA replication
GO:0006287 IEA base-excision repair, gap-filling
GO:0007568 IMP aging
GO:0042645 IEA mitochondrial nucleoid
GO:0070062 IEA extracellular vesicular exosome
GO:0071897 IEA DNA biosynthetic process
GO:0090305 IDA nucleic acid phosphodiester bond hydrolysis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000060951 polg polymerase (DNA directed), gamma protein_coding Danio_rerio
ENSG00000140521 POLG polymerase (DNA directed), gamma protein_coding Homo_sapiens

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