C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: cytochrome P450, family 7, subfamily b, polypeptide 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000039519 Cyp7b1 10090 - 3:18071950-18243338 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000035625 Cyp7b1-201 18071950-18243338 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000035625
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000035625 0.949±0.86 5.191±1.95 2.698±0.52 1.380±0.88 2.672±2.55 0.478±0.40 0.322±0.05 1.694±0.77 8.585±9.24 1.716±1.45 0.075±0.05 5.075±4.30 0.251±0.21 0.116±0.05

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007NS CIL_0007NS_0006 UCNEbase 3:16820555-18937830
CIL_0008AX CIL_0008AX_0002 VISTA 3:17757876-18358899
CIL_0008IQ CIL_0008IQ_0002 VISTA 3:18041076-18642204
CIL_00031Q CIL_00031Q_0002 CGP 3:18054174-18243338
CIL_0003G9 CIL_0003G9_0002 CGP 3:18071950-19163065

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005506 IEA iron ion binding
GO:0005783 IEA endoplasmic reticulum
GO:0006699 IEA bile acid biosynthetic process
GO:0007586 TAS digestion
GO:0008203 IEA cholesterol metabolic process
GO:0008396 IDA oxysterol 7-alpha-hydroxylase activity
GO:0016020 IEA membrane
GO:0020037 IEA heme binding
GO:0033147 IMP negative regulation of intracellular estrogen receptor signaling pathway
GO:0033783 IEA 25-hydroxycholesterol 7alpha-hydroxylase activity
GO:0043231 TAS intracellular membrane-bounded organelle
GO:0050679 IMP positive regulation of epithelial cell proliferation
GO:0055114 IEA oxidation-reduction process
GO:0060740 IMP prostate gland epithelium morphogenesis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000008858 cyp7c1 cytochrome P450, family 7, subfamily C, polypeptide 1 protein_coding Danio_rerio
ENSG00000172817 CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1 protein_coding Homo_sapiens

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