C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000040296 Ddx58 10090 - 4:40203773-40239828 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000037907 Ddx58-001 40204849-40239828 protein_coding
  ENSMUST00000127026 Ddx58-004 40223876-40239722 processed_transcript
  ENSMUST00000135966 Ddx58-010 40208771-40214072 processed_transcript
  ENSMUST00000136435 Ddx58-009 40203773-40208543 processed_transcript
  ENSMUST00000137903 Ddx58-005 40203777-40220600 processed_transcript
  ENSMUST00000139110 Ddx58-007 40226570-40228356 processed_transcript
  ENSMUST00000139583 Ddx58-003 40223431-40239755 processed_transcript
  ENSMUST00000140616 Ddx58-008 40208185-40208795 processed_transcript
  ENSMUST00000142055 Ddx58-006 40208853-40239700 protein_coding
  ENSMUST00000149539 Ddx58-002 40227059-40239825 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000037907ENSMUST00000137903ENSMUST00000142055
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000037907 7.154±1.19 11.266±1.33 3.984±0.86 0.515±0.19 8.126±1.94 2.912±0.61 1.925±0.36 5.968±0.42 3.255±1.84 9.756±0.61 0.423±0.16 6.348±1.78 8.953±1.58 0.820±0.30
ENSMUST00000137903 N/A N/A 1.545±0.50 0.250±0.07 2.191±0.65 1.021±0.00 N/A N/A 0.836±0.51 N/A 0.164±0.02 2.070±0.41 2.410±0.78 0.071±0.00
ENSMUST00000142055 N/A N/A N/A N/A 5.269±0.00 N/A N/A N/A N/A N/A 0.226±0.00 1.995±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000437 CIL_000437_0002 CGP 4:40143081-40239828
CIL_00065D CIL_00065D_0002 CGP 4:40203773-40269850

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002230 ISS positive regulation of defense response to virus by host
GO:0003690 IDA double-stranded DNA binding
GO:0003725 IDA double-stranded RNA binding
GO:0003727 IDA single-stranded RNA binding
GO:0004386 IEA helicase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005737 IEA cytoplasm
GO:0005829 TAS cytosol
GO:0005923 ISS tight junction
GO:0008152 IEA metabolic process
GO:0008270 ISS zinc ion binding
GO:0009597 IEA detection of virus
GO:0009615 IMP response to virus
GO:0015629 ISS actin cytoskeleton
GO:0030334 ISS regulation of cell migration
GO:0032587 ISS ruffle membrane
GO:0032727 ISS positive regulation of interferon-alpha production
GO:0032728 IMP positive regulation of interferon-beta production
GO:0039529 IEA RIG-I signaling pathway
GO:0042802 IEA identical protein binding
GO:0042993 IEA positive regulation of transcription factor import into nucleus
GO:0043330 IMP response to exogenous dsRNA
GO:0045087 IMP innate immune response
GO:0045944 IEA positive regulation of transcription from RNA polymerase II promoter

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000107201 DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 protein_coding Homo_sapiens

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