C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000037907 Ddx58-001 ENSMUSG00000040296 10090 - 4:40204849-40239828 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000037907
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000037907 7.154±1.19 11.266±1.33 3.984±0.86 0.515±0.19 8.126±1.94 2.912±0.61 1.925±0.36 5.968±0.42 3.255±1.84 9.756±0.61 0.423±0.16 6.348±1.78 8.953±1.58 0.820±0.30

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000437 CIL_000437_0002 CGP 4:40143081-40239828
CIL_00065D CIL_00065D_0002 CGP 4:40203773-40269850

Gene Ontology

GO IDEvidence TypeGO Description
GO:0002230 ISS positive regulation of defense response to virus by host
GO:0003690 IDA double-stranded DNA binding
GO:0003725 IDA double-stranded RNA binding
GO:0003727 IDA single-stranded RNA binding
GO:0004386 IEA helicase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005737 IEA cytoplasm
GO:0005829 TAS cytosol
GO:0005923 ISS tight junction
GO:0008152 IEA metabolic process
GO:0008270 ISS zinc ion binding
GO:0009597 IEA detection of virus
GO:0009615 IMP response to virus
GO:0015629 ISS actin cytoskeleton
GO:0030334 ISS regulation of cell migration
GO:0032587 ISS ruffle membrane
GO:0032727 ISS positive regulation of interferon-alpha production
GO:0032728 IMP positive regulation of interferon-beta production
GO:0039529 IEA RIG-I signaling pathway
GO:0042802 IEA identical protein binding
GO:0042993 IEA positive regulation of transcription factor import into nucleus
GO:0043330 IMP response to exogenous dsRNA
GO:0045087 IMP innate immune response
GO:0045944 IEA positive regulation of transcription from RNA polymerase II promoter

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000379868 DDX58-002 protein_coding Homo_sapiens 0 1578
ENST00000379883 DDX58-001 protein_coding Homo_sapiens 0 2026

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