C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: MIS12 homolog (yeast)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000040599 Mis12 10090 + 11:71019611-71027371 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000048807 Mis12-001 71019611-71027371 protein_coding
  ENSMUST00000133413 Mis12-004 71019611-71025178 protein_coding
  ENSMUST00000136137 Mis12-006 71019891-71025195 protein_coding
  ENSMUST00000143762 Mis12-002 71019862-71025158 protein_coding
  ENSMUST00000155236 Mis12-005 71019859-71025167 protein_coding
  ENSMUST00000164220 Mis12-003 71019611-71026066 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000048807
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000048807 3.414±1.08 1.394±0.00 6.618±0.09 7.896±0.18 2.963±0.77 2.302±0.09 1.818±0.28 3.215±0.77 11.515±3.99 4.091±0.41 1.224±0.33 3.211±0.41 7.999±2.91 2.608±0.64

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000FL CIL_0000FL_0002 CGP 11:70984091-71019841
CIL_0002PM CIL_0002PM_0002 CGP 11:71007164-71027371
CIL_0002G8 CIL_0002G8_0002 CGP 11:71019611-71144704

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000444 ISS MIS12/MIND type complex
GO:0003674 ND molecular_function
GO:0005515 IEA protein binding
GO:0005634 IEA nucleus
GO:0007059 ISS chromosome segregation
GO:0007067 IEA mitotic nuclear division
GO:0051382 ISS kinetochore assembly

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000026454 MIS12 MIS12 kinetochore complex component protein_coding Danio_rerio
ENSG00000167842 MIS12 MIS12 kinetochore complex component protein_coding Homo_sapiens

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