C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: MIS12 kinetochore complex component
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000167842 MIS12 9606 + 17:5486285-5490814 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000381165 MIS12-001 5486927-5490814 protein_coding
  ENST00000573759 MIS12-002 5486396-5490737 protein_coding
  ENST00000574186 MIS12-005 5486577-5487159 processed_transcript
  ENST00000576570 MIS12-004 5486385-5488935 protein_coding
  ENST00000576988 MIS12-003 5486285-5489237 protein_coding
  ENST00000611091 MIS12-201 5486374-5490808 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000381165ENST00000573759ENST00000611091
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000381165 N/A 3.781±0.00 4.191±0.00 2.703±0.00 N/A 0.288±0.00 0.603±0.00 N/A N/A 0.441±0.00 N/A N/A 6.432±0.00
ENST00000573759 2.337±0.00 N/A 0.686±0.00 2.624±0.43 2.262±0.00 2.112±0.00 4.004±2.96 2.960±0.00 3.775±0.00 1.114±0.00 4.086±0.36 2.353±0.05 N/A
ENST00000611091 N/A N/A N/A 1.345±0.00 N/A N/A N/A 0.578±0.00 N/A N/A 2.766±1.30 2.195±0.00 10.444±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000FL CIL_0000FL_0001 CGP 17:5440912-5486811
CIL_0002PM CIL_0002PM_0001 CGP 17:5471251-5490814
CIL_0002G8 CIL_0002G8_0001 CGP 17:5486285-5619424

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000278 TAS mitotic cell cycle
GO:0000444 IDA MIS12/MIND type complex
GO:0000775 IEA chromosome, centromeric region
GO:0005515 IPI protein binding
GO:0005634 IEA:IDA nucleus
GO:0005829 TAS cytosol
GO:0007049 IEA cell cycle
GO:0007059 IMP chromosome segregation
GO:0007067 IEA mitotic nuclear division
GO:0051382 IDA kinetochore assembly

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000026454 MIS12 MIS12 kinetochore complex component protein_coding Danio_rerio
ENSMUSG00000040599 Mis12 MIS12 homolog (yeast) protein_coding Mus_musculus

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