C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: beta-site APP-cleaving enzyme 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000040605 Bace2 10090 + 16:97356728-97439012 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000047275 Bace2-201 97356728-97439012 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000047275
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000047275 4.427±1.82 5.755±2.08 15.755±2.39 0.279±0.06 3.387±0.93 27.823±5.79 2.348±0.17 1.299±0.13 1.091±0.50 5.477±0.78 0.296±0.09 17.289±6.92 0.599±0.22 0.243±0.11

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001CW CIL_0001CW_0003 CGP 16:96592079-97439012

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004190 ISS aspartic-type endopeptidase activity
GO:0005768 IEA endosome
GO:0005783 IEA endoplasmic reticulum
GO:0005794 ISS Golgi apparatus
GO:0006509 ISS membrane protein ectodomain proteolysis
GO:0016021 IEA integral component of membrane
GO:0042985 ISS negative regulation of amyloid precursor protein biosynthetic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000044781 bace2 beta-site APP-cleaving enzyme 2 protein_coding Danio_rerio
ENSDARG00000086067 BACE2 (2 of 2) beta-site APP-cleaving enzyme 2 protein_coding Danio_rerio
ENSG00000182240 BACE2 beta-site APP-cleaving enzyme 2 protein_coding Homo_sapiens

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