C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: beta-site APP-cleaving enzyme 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000047275 Bace2-201 ENSMUSG00000040605 10090 + 16:97356728-97439012 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000047275
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000047275 4.427±1.82 5.755±2.08 15.755±2.39 0.279±0.06 3.387±0.93 27.823±5.79 2.348±0.17 1.299±0.13 1.091±0.50 5.477±0.78 0.296±0.09 17.289±6.92 0.599±0.22 0.243±0.11

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001CW CIL_0001CW_0003 CGP 16:96592079-97439012

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004190 ISS aspartic-type endopeptidase activity
GO:0005768 IEA endosome
GO:0005783 IEA endoplasmic reticulum
GO:0005794 ISS Golgi apparatus
GO:0006509 ISS membrane protein ectodomain proteolysis
GO:0016021 IEA integral component of membrane
GO:0042985 ISS negative regulation of amyloid precursor protein biosynthetic process

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000328735 BACE2-003 protein_coding Homo_sapiens 0 1094
ENST00000330333 BACE2-001 protein_coding Homo_sapiens 0 1491
ENST00000347667 BACE2-002 protein_coding Homo_sapiens 0 972
ENST00000463674 BACE2-008 processed_transcript Homo_sapiens 0 946
ENST00000465326 BACE2-006 processed_transcript Homo_sapiens 0 983
ENST00000466122 BACE2-004 processed_transcript Homo_sapiens 0 1208
ENST00000487994 BACE2-007 processed_transcript Homo_sapiens 0 1055
ENST00000491838 BACE2-009 retained_intron Homo_sapiens 0 749

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