C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: distal-less homeobox 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000041911 Dlx1 10090 + 2:71528113-71533981 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000037119 Dlx1-001 71528113-71533980 protein_coding
  ENSMUST00000126400 Dlx1-005 71528683-71530065 protein_coding
  ENSMUST00000145088 Dlx1-003 71529947-71533981 retained_intron
  ENSMUST00000145444 Dlx1-002 71529853-71532519 nonsense_mediated_decay
  ENSMUST00000152711 Dlx1-004 71529101-71530231 protein_coding
  ENSMUST00000172629 Dlx1-006 71530780-71532689 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000037119ENSMUST00000126400ENSMUST00000145088ENSMUST00000145444ENSMUST00000152711ENSMUST00000172629
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000037119 N/A 0.061±0.01 N/A 12.719±4.81 0.035±0.00 0.040±0.01 0.046±0.02 0.008±0.00 0.055±0.00 0.030±0.01 0.012±0.00 0.030±0.00 N/A 0.041±0.01
ENSMUST00000126400 N/A N/A N/A N/A N/A 0.142±0.10 0.043±0.00 N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000145088 N/A 0.040±0.01 0.031±0.00 20.865±14.54 0.041±0.00 0.029±0.01 N/A 0.036±0.00 0.036±0.00 N/A N/A 0.060±0.01 0.017±0.01 0.056±0.03
ENSMUST00000145444 0.049±0.00 0.182±0.09 N/A N/A 0.080±0.00 0.098±0.03 0.052±0.00 N/A N/A 0.110±0.04 N/A 0.143±0.06 N/A 0.141±0.10
ENSMUST00000152711 N/A 0.291±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.340±0.00 N/A N/A
ENSMUST00000172629 N/A 0.373±0.13 N/A 18.207±0.00 N/A 0.164±0.11 0.093±0.00 0.090±0.03 0.054±0.00 0.155±0.15 N/A 0.156±0.05 0.089±0.04 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007RB CIL_0007RB_0003 VISTA 2:71118479-71722071
CIL_0008A7 CIL_0008A7_0002 VISTA 2:71118555-71719483
CIL_0008C9 CIL_0008C9_0002 VISTA 2:71216484-71818219
CIL_0009AY CIL_0009AY_0002 VISTA 2:71227336-71828847
CIL_0008AZ CIL_0008AZ_0002 VISTA 2:71235378-71836557
CIL_0008B0 CIL_0008B0_0002 VISTA 2:71237156-71838581
CIL_0007JJ CIL_0007JJ_002C UCNEbase 2:71244754-71538420
CIL_0004K6 CIL_0004K6_0002 CGP 2:71453276-71533981
CIL_00062L CIL_00062L_0003 CGP 2:71528113-71546754

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IGI negative regulation of transcription from RNA polymerase II promoter
GO:0003677 IDA DNA binding
GO:0003682 IDA chromatin binding
GO:0005634 IDA nucleus
GO:0006357 IGI regulation of transcription from RNA polymerase II promoter
GO:0009954 IGI proximal/distal pattern formation
GO:0021544 IGI subpallium development
GO:0021766 IGI hippocampus development
GO:0021879 IGI forebrain neuron differentiation
GO:0021882 IGI regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment
GO:0021892 IGI cerebral cortex GABAergic interneuron differentiation
GO:0021893 IGI cerebral cortex GABAergic interneuron fate commitment
GO:0030154 IMP cell differentiation
GO:0042475 IGI odontogenesis of dentin-containing tooth
GO:0043524 IMP negative regulation of neuron apoptotic process
GO:0043565 IEA sequence-specific DNA binding
GO:0045746 IGI negative regulation of Notch signaling pathway
GO:0048706 IGI embryonic skeletal system development
GO:0048715 IGI negative regulation of oligodendrocyte differentiation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000013125 dlx1a distal-less homeobox gene 1a protein_coding Danio_rerio
ENSG00000144355 DLX1 distal-less homeobox 1 protein_coding Homo_sapiens

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