C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: inhibitor of kappaB kinase epsilon
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000042349 Ikbke 10090 - 1:131254343-131279606 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000062108 Ikbke-001 131254597-131279606 protein_coding
  ENSMUST00000159195 Ikbke-004 131273791-131276713 protein_coding
  ENSMUST00000160748 Ikbke-007 131259020-131266288 retained_intron
  ENSMUST00000161764 Ikbke-002 131254602-131276951 protein_coding
  ENSMUST00000162285 Ikbke-005 131270901-131272541 retained_intron
  ENSMUST00000162437 Ikbke-003 131254343-131265131 retained_intron
  ENSMUST00000163029 Ikbke-006 131263339-131270544 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000062108ENSMUST00000159195ENSMUST00000160748ENSMUST00000161764ENSMUST00000162437ENSMUST00000163029
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000062108 6.734±1.57 4.060±0.90 10.343±0.71 0.267±0.08 12.496±3.88 15.490±1.19 0.763±0.21 2.293±0.58 2.154±0.86 4.016±0.42 0.277±0.18 4.949±1.38 1.061±0.68 0.364±0.15
ENSMUST00000159195 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.553±0.00 0.590±0.00
ENSMUST00000160748 N/A N/A N/A 0.289±0.00 N/A N/A N/A N/A N/A N/A 0.174±0.00 N/A N/A 0.144±0.00
ENSMUST00000161764 N/A N/A 1.264±0.00 N/A N/A N/A 0.298±0.00 0.829±0.00 4.084±1.34 N/A 0.095±0.00 1.734±0.50 0.530±0.45 0.108±0.03
ENSMUST00000162437 0.849±0.00 N/A 1.018±0.13 0.063±0.02 1.314±0.00 N/A 0.098±0.00 N/A N/A N/A 0.036±0.02 0.878±0.01 0.069±0.04 0.067±0.03
ENSMUST00000163029 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.429±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004IR CIL_0004IR_0002 CGP 1:131176410-131279606
CIL_0005VZ CIL_0005VZ_0002 CGP 1:131254343-131527352

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004704 ISS NF-kappaB-inducing kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 ISS nucleus
GO:0005737 ISS cytoplasm
GO:0006468 ISS protein phosphorylation
GO:0007252 IDA:IEA I-kappaB phosphorylation
GO:0008384 IDA IkappaB kinase activity
GO:0008630 ISS intrinsic apoptotic signaling pathway in response to DNA damage
GO:0016605 ISS PML body
GO:0038061 IEA NIK/NF-kappaB signaling
GO:0043123 ISS positive regulation of I-kappaB kinase/NF-kappaB signaling

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000070606 ikbke inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon protein_coding Danio_rerio
ENSG00000263528 IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon protein_coding Homo_sapiens

Loading