C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: inhibitor of kappaB kinase epsilon
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000062108 Ikbke-001 ENSMUSG00000042349 10090 - 1:131254597-131279606 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000062108
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000062108 6.734±1.57 4.060±0.90 10.343±0.71 0.267±0.08 12.496±3.88 15.490±1.19 0.763±0.21 2.293±0.58 2.154±0.86 4.016±0.42 0.277±0.18 4.949±1.38 1.061±0.68 0.364±0.15

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004IR CIL_0004IR_0002 CGP 1:131176410-131279606
CIL_0005VZ CIL_0005VZ_0002 CGP 1:131254343-131527352

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004704 ISS NF-kappaB-inducing kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 ISS nucleus
GO:0005737 ISS cytoplasm
GO:0006468 ISS protein phosphorylation
GO:0007252 IDA:IEA I-kappaB phosphorylation
GO:0008384 IDA IkappaB kinase activity
GO:0008630 ISS intrinsic apoptotic signaling pathway in response to DNA damage
GO:0016605 ISS PML body
GO:0038061 IEA NIK/NF-kappaB signaling
GO:0043123 ISS positive regulation of I-kappaB kinase/NF-kappaB signaling

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000578328 IKBKE-004 protein_coding Homo_sapiens 0 1947
ENST00000579827 IKBKE-006 protein_coding Homo_sapiens 0 488
ENST00000581977 IKBKE-001 protein_coding Homo_sapiens 0 2028
ENST00000584998 IKBKE-003 protein_coding Homo_sapiens 0 1814
ENST00000605726 IKBKE-005 protein_coding Homo_sapiens 0 508
ENST00000605818 IKBKE-002 retained_intron Homo_sapiens 0 990

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