C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: CASP2 and RIPK1 domain containing adaptor with death domain
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000045867 Cradd 10090 - 10:95174746-95324097 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000053594 Cradd-201 95174746-95324097 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000053594
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000053594 4.362±0.72 11.866±1.48 4.171±0.27 2.465±0.96 7.218±2.52 6.640±0.51 3.425±1.65 6.060±1.74 5.700±4.25 5.057±1.78 3.290±0.49 11.596±4.43 1.320±0.39 0.267±0.11

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003XW CIL_0003XW_0002 CGP 10:94790866-95324097
CIL_0004YM CIL_0004YM_0002 CGP 10:95174746-95417180

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002020 IEA protease binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0006919 IGI activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0006977 IEA DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
GO:0030674 IEA protein binding, bridging
GO:0070513 IEA death domain binding
GO:0071260 IEA cellular response to mechanical stimulus
GO:2001235 IGI positive regulation of apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000028192 cradd CASP2 and RIPK1 domain containing adaptor with death domain protein_coding Danio_rerio
ENSG00000169372 CRADD CASP2 and RIPK1 domain containing adaptor with death domain protein_coding Homo_sapiens

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