C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: prostaglandin-endoperoxide synthase 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000047250 Ptgs1 10090 + 2:36230426-36252272 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000062069 Ptgs1-001 36230426-36252272 protein_coding
  ENSMUST00000133777 Ptgs1-005 36242475-36245205 processed_transcript
  ENSMUST00000144319 Ptgs1-002 36230556-36238063 processed_transcript
  ENSMUST00000149930 Ptgs1-003 36236249-36240742 processed_transcript
  ENSMUST00000151351 Ptgs1-004 36240713-36241468 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000062069ENSMUST00000133777ENSMUST00000144319ENSMUST00000149930
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000062069 7.631±1.44 5.138±1.91 20.297±1.22 0.865±0.24 3.622±1.21 10.109±1.63 3.438±0.37 6.667±0.82 5.103±2.45 18.638±6.22 0.805±0.11 4.516±1.09 3.232±2.94 0.912±1.01
ENSMUST00000133777 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.322±0.00
ENSMUST00000144319 N/A 4.509±0.72 N/A N/A 2.609±0.00 7.714±0.00 N/A N/A N/A N/A N/A 2.744±0.00 N/A N/A
ENSMUST00000149930 N/A N/A N/A N/A 4.724±0.13 9.860±0.00 N/A N/A N/A N/A N/A 4.003±0.00 N/A 0.342±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006NA CIL_0006NA_0002 CGP 2:36136389-36252272

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001516 IMP prostaglandin biosynthetic process
GO:0001750 IDA photoreceptor outer segment
GO:0004601 IEA peroxidase activity
GO:0004666 IEA prostaglandin-endoperoxide synthase activity
GO:0005737 IDA cytoplasm
GO:0005783 IEA endoplasmic reticulum
GO:0006693 IMP prostaglandin metabolic process
GO:0006954 IEA inflammatory response
GO:0006979 IEA response to oxidative stress
GO:0008217 IMP regulation of blood pressure
GO:0016020 IEA membrane
GO:0019371 IEA cyclooxygenase pathway
GO:0020037 IEA heme binding
GO:0030216 NAS keratinocyte differentiation
GO:0042127 IGI regulation of cell proliferation
GO:0046872 IEA metal ion binding
GO:0051213 IEA dioxygenase activity
GO:0055114 IEA oxidation-reduction process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000052148 ptgs1 prostaglandin-endoperoxide synthase 1 protein_coding Danio_rerio
ENSG00000095303 PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) protein_coding Homo_sapiens

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