C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: prostaglandin-endoperoxide synthase 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000062069 Ptgs1-001 ENSMUSG00000047250 10090 + 2:36230426-36252272 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000062069
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000062069 7.631±1.44 5.138±1.91 20.297±1.22 0.865±0.24 3.622±1.21 10.109±1.63 3.438±0.37 6.667±0.82 5.103±2.45 18.638±6.22 0.805±0.11 4.516±1.09 3.232±2.94 0.912±1.01

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006NA CIL_0006NA_0002 CGP 2:36136389-36252272

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001516 IMP prostaglandin biosynthetic process
GO:0001750 IDA photoreceptor outer segment
GO:0004601 IEA peroxidase activity
GO:0004666 IEA prostaglandin-endoperoxide synthase activity
GO:0005737 IDA cytoplasm
GO:0005783 IEA endoplasmic reticulum
GO:0006693 IMP prostaglandin metabolic process
GO:0006954 IEA inflammatory response
GO:0006979 IEA response to oxidative stress
GO:0008217 IMP regulation of blood pressure
GO:0016020 IEA membrane
GO:0019371 IEA cyclooxygenase pathway
GO:0020037 IEA heme binding
GO:0030216 NAS keratinocyte differentiation
GO:0042127 IGI regulation of cell proliferation
GO:0046872 IEA metal ion binding
GO:0051213 IEA dioxygenase activity
GO:0055114 IEA oxidation-reduction process

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000010028 ptgs2b-001 protein_coding Danio_rerio 1e-30 139
ENST00000223423 PTGS1-002 protein_coding Homo_sapiens 0 1262
ENST00000362012 PTGS1-001 protein_coding Homo_sapiens 0 1919
ENST00000373698 PTGS1-201 protein_coding Homo_sapiens 0 1868
ENST00000540753 PTGS1-202 protein_coding Homo_sapiens 0 1208
ENST00000614910 PTGS1-203 protein_coding Homo_sapiens 0 1397
ENST00000619306 PTGS1-204 protein_coding Homo_sapiens 0 1919

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