C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: TGFB-induced factor homeobox 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000047407 Tgif1 10090 - 17:70844205-70853546 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000059775 Tgif1-001 70844205-70851207 protein_coding
  ENSMUST00000118283 Tgif1-003 70844211-70853546 protein_coding
  ENSMUST00000125329 Tgif1-007 70848374-70849807 processed_transcript
  ENSMUST00000127719 Tgif1-004 70844728-70849790 protein_coding
  ENSMUST00000132825 Tgif1-005 70846295-70851131 processed_transcript
  ENSMUST00000134654 Tgif1-006 70846181-70849644 protein_coding
  ENSMUST00000135007 Tgif1-009 70844981-70847170 protein_coding
  ENSMUST00000156484 Tgif1-008 70844869-70846326 protein_coding
  ENSMUST00000166395 Tgif1-002 70844211-70851734 protein_coding
  ENSMUST00000172229 Tgif1-201 70844205-70849790 protein_coding
  ENSMUST00000186358 Tgif1-011 70844211-70851069 protein_coding
  ENSMUST00000190687 Tgif1-010 70846670-70849814 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000059775ENSMUST00000118283ENSMUST00000127719ENSMUST00000135007ENSMUST00000166395ENSMUST00000172229ENSMUST00000186358ENSMUST00000190687
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000059775 9.697±5.56 7.706±2.06 16.338±1.22 1.973±0.00 8.032±1.91 13.837±1.30 1.748±0.44 4.070±0.51 4.743±1.72 4.561±0.65 1.371±0.48 30.580±7.23 3.435±3.47 6.171±0.65
ENSMUST00000118283 5.103±3.10 6.882±2.29 7.697±0.76 1.597±1.06 6.454±4.27 6.914±2.64 1.444±0.32 2.256±0.77 1.847±0.22 2.559±0.50 0.693±0.26 20.448±7.62 3.108±0.86 10.618±4.70
ENSMUST00000127719 N/A 5.076±0.38 N/A 1.906±0.00 3.580±0.55 6.937±1.60 1.574±0.00 N/A 2.728±0.44 2.455±0.00 N/A 14.619±3.00 N/A N/A
ENSMUST00000135007 N/A N/A N/A 0.123±0.00 N/A N/A N/A N/A N/A N/A N/A 7.636±0.00 0.360±0.00 0.807±0.00
ENSMUST00000166395 N/A N/A N/A N/A N/A N/A 0.618±0.00 N/A N/A N/A 0.482±0.14 N/A N/A N/A
ENSMUST00000172229 N/A 3.714±0.54 N/A N/A N/A N/A N/A 2.276±0.25 1.669±0.26 2.529±0.18 N/A 13.250±4.76 2.665±0.00 1.494±0.00
ENSMUST00000186358 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 14.201±0.00 3.570±2.61 1.021±0.00
ENSMUST00000190687 N/A N/A 3.208±0.46 0.261±0.23 N/A N/A N/A N/A 0.944±0.13 1.022±0.00 0.227±0.10 4.126±1.61 N/A 0.159±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006KX CIL_0006KX_0002 CGP 17:69969073-70853546

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IGI negative regulation of transcription from RNA polymerase II promoter
GO:0000978 IEA RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001078 IEA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
GO:0001843 IMP neural tube closure
GO:0003677 IEA DNA binding
GO:0003682 IDA chromatin binding
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0006351 IEA transcription, DNA-templated
GO:0007368 IMP determination of left/right symmetry
GO:0008285 IMP negative regulation of cell proliferation
GO:0009953 IMP dorsal/ventral pattern formation
GO:0010470 IGI regulation of gastrulation
GO:0010629 IEA negative regulation of gene expression
GO:0038092 IGI nodal signaling pathway
GO:0042493 IEA response to drug
GO:0045666 IDA positive regulation of neuron differentiation
GO:0048146 IMP positive regulation of fibroblast proliferation
GO:0048387 IMP negative regulation of retinoic acid receptor signaling pathway
GO:0060041 IDA retina development in camera-type eye
GO:0070410 IEA co-SMAD binding
GO:0071363 IEA cellular response to growth factor stimulus

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000059337 tgif1 transforming growth factor-beta-induced factor 1 protein_coding Danio_rerio
ENSG00000177426 TGIF1 TGFB-induced factor homeobox 1 protein_coding Homo_sapiens

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