C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: brain derived neurotrophic factor
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000048482 Bdnf 10090 + 2:109674700-109727007 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000053317 Bdnf-001 109674700-109727007 protein_coding
  ENSMUST00000111042 Bdnf-010 109709383-109727007 protein_coding
  ENSMUST00000111043 Bdnf-009 109694409-109727007 protein_coding
  ENSMUST00000111044 Bdnf-008 109694469-109727007 protein_coding
  ENSMUST00000111045 Bdnf-007 109693563-109727007 protein_coding
  ENSMUST00000111046 Bdnf-005 109677032-109727007 protein_coding
  ENSMUST00000111047 Bdnf-003 109675897-109727007 protein_coding
  ENSMUST00000111049 Bdnf-004 109675897-109727007 protein_coding
  ENSMUST00000111050 Bdnf-006 109692436-109727007 protein_coding
  ENSMUST00000111051 Bdnf-002 109675897-109727007 protein_coding
  ENSMUST00000176893 Bdnf-011 109693027-109727007 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000053317ENSMUST00000111042ENSMUST00000111045ENSMUST00000111047ENSMUST00000111050ENSMUST00000111051ENSMUST00000176893
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000053317 N/A N/A N/A 0.303±0.17 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000111042 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.023±0.00 0.115±0.02
ENSMUST00000111045 0.184±0.07 0.056±0.02 2.450±1.08 0.472±0.07 0.859±0.26 0.295±0.14 0.740±0.17 1.124±0.14 0.166±0.17 5.700±0.77 0.132±0.00 0.829±0.42 0.094±0.01 N/A
ENSMUST00000111047 N/A N/A N/A 0.363±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000111050 N/A N/A N/A 0.364±0.26 N/A N/A 0.107±0.00 N/A N/A N/A 0.083±0.00 0.061±0.00 0.013±0.00 N/A
ENSMUST00000111051 N/A N/A N/A 0.129±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000176893 N/A N/A N/A 0.451±0.00 0.331±0.00 N/A N/A N/A 0.037±0.00 N/A 0.068±0.03 0.112±0.06 0.034±0.02 0.100±0.06

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001657 IDA ureteric bud development
GO:0001662 IMP behavioral fear response
GO:0001666 IEA response to hypoxia
GO:0002544 IEA chronic inflammatory response
GO:0005102 IEA receptor binding
GO:0005169 IEA neurotrophin TRKB receptor binding
GO:0005515 IPI protein binding
GO:0005576 TAS extracellular region
GO:0005615 IEA extracellular space
GO:0005737 IDA cytoplasm
GO:0005788 TAS endoplasmic reticulum lumen
GO:0006120 IEA mitochondrial electron transport, NADH to ubiquinone
GO:0007214 IDA gamma-aminobutyric acid signaling pathway
GO:0007399 IEA nervous system development
GO:0007406 IDA negative regulation of neuroblast proliferation
GO:0007411 IMP axon guidance
GO:0007412 IMP axon target recognition
GO:0007611 IMP learning or memory
GO:0007612 IEA learning
GO:0007623 IEP circadian rhythm
GO:0007631 IMP feeding behavior
GO:0008021 IEA synaptic vesicle
GO:0008038 IMP neuron recognition
GO:0008083 IEA growth factor activity
GO:0009416 IEA response to light stimulus
GO:0009642 IEA response to light intensity
GO:0009725 IEA response to hormone
GO:0010996 IEA response to auditory stimulus
GO:0014047 IPI glutamate secretion
GO:0014076 IEA response to fluoxetine
GO:0014823 IEA response to activity
GO:0016023 IDA cytoplasmic membrane-bounded vesicle
GO:0016358 IMP dendrite development
GO:0019222 IMP regulation of metabolic process
GO:0021675 IMP nerve development
GO:0030061 IEA mitochondrial crista
GO:0030424 IEA axon
GO:0030425 IEA dendrite
GO:0030516 IEA regulation of axon extension
GO:0031667 IEA response to nutrient levels
GO:0032094 IEA response to food
GO:0032229 IDA negative regulation of synaptic transmission, GABAergic
GO:0033138 IDA positive regulation of peptidyl-serine phosphorylation
GO:0033189 IEA response to vitamin A
GO:0034612 IEA response to tumor necrosis factor
GO:0035864 IEA response to potassium ion
GO:0042490 IGI mechanoreceptor differentiation
GO:0042493 IMP response to drug
GO:0042596 IMP fear response
GO:0043025 IEA neuronal cell body
GO:0043066 IDA negative regulation of apoptotic process
GO:0043195 IEA terminal bouton
GO:0043204 IEA perikaryon
GO:0043523 IDA regulation of neuron apoptotic process
GO:0043524 IMP negative regulation of neuron apoptotic process
GO:0045666 IDA positive regulation of neuron differentiation
GO:0045843 IEA negative regulation of striated muscle tissue development
GO:0046668 IDA regulation of retinal cell programmed cell death
GO:0048167 IDA regulation of synaptic plasticity
GO:0048169 IEA regulation of long-term neuronal synaptic plasticity
GO:0048170 IEA positive regulation of long-term neuronal synaptic plasticity
GO:0048172 IEA regulation of short-term neuronal synaptic plasticity
GO:0048471 IDA perinuclear region of cytoplasm
GO:0048675 IDA axon extension
GO:0048839 IMP inner ear development
GO:0050890 IEA cognition
GO:0051602 IEA response to electrical stimulus
GO:0051965 IEA positive regulation of synapse assembly
GO:0055093 IEA response to hyperoxia
GO:0060079 IEA regulation of excitatory postsynaptic membrane potential
GO:0060548 IMP negative regulation of cell death
GO:0061193 IMP taste bud development
GO:0071356 IEA cellular response to tumor necrosis factor
GO:0071874 IEA cellular response to norepinephrine stimulus
GO:0072347 IEA response to anesthetic
GO:0097484 IDA dendrite extension
GO:1901215 IEA negative regulation of neuron death
GO:1902065 IEA response to L-glutamate
GO:1990089 IEA response to nerve growth factor
GO:1990090 IEA cellular response to nerve growth factor stimulus
GO:1990138 IEA neuron projection extension

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000018817 bdnf brain-derived neurotrophic factor protein_coding Danio_rerio
ENSG00000176697 BDNF brain-derived neurotrophic factor protein_coding Homo_sapiens

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