C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: three prime repair exonuclease 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000049734 Trex1 10090 - 9:109057933-109060338 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000061973 Trex1-001 109057933-109059734 protein_coding
  ENSMUST00000112053 Trex1-002 109057938-109059251 protein_coding
  ENSMUST00000128062 Trex1-003 109058470-109060338 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000061973ENSMUST00000112053ENSMUST00000128062
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000061973 8.409±0.39 13.455±0.68 6.174±1.58 8.187±2.50 N/A 9.101±0.00 5.218±0.24 5.221±1.03 3.076±0.00 N/A 3.551±0.28 13.709±2.25 N/A N/A
ENSMUST00000112053 20.745±3.24 37.699±5.29 10.714±1.36 7.747±0.59 57.350±18.03 23.001±2.66 9.812±2.96 12.027±1.72 12.151±2.71 30.281±2.54 5.685±1.36 32.668±9.06 5.444±2.47 2.715±0.33
ENSMUST00000128062 N/A N/A N/A 6.066±0.00 N/A N/A N/A N/A N/A N/A N/A 6.775±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002UL CIL_0002UL_0002 CGP 9:109057933-109074124

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000738 IEA DNA catabolic process, exonucleolytic
GO:0003690 IDA double-stranded DNA binding
GO:0003697 IDA single-stranded DNA binding
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0005730 IEA nucleolus
GO:0005783 IEA endoplasmic reticulum
GO:0006259 IDA DNA metabolic process
GO:0008296 IDA 3'-5'-exodeoxyribonuclease activity
GO:0008408 ISS 3'-5' exonuclease activity
GO:0008853 IEA exodeoxyribonuclease III activity
GO:0016020 IEA membrane
GO:0032405 ISA MutLalpha complex binding
GO:0032407 ISA MutSalpha complex binding
GO:0032558 IDA adenyl deoxyribonucleotide binding
GO:0035458 IDA cellular response to interferon-beta
GO:0042803 IPI protein homodimerization activity
GO:0046872 IEA metal ion binding
GO:0090305 IEA nucleic acid phosphodiester bond hydrolysis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000213689 TREX1 three prime repair exonuclease 1 protein_coding Homo_sapiens

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