C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: Down syndrome cell adhesion molecule
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000050272 Dscam 10090 - 16:96592079-97170752 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000056102 Dscam-001 96592079-97170752 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000056102
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000056102 0.038±0.04 0.009±0.00 0.004±0.00 7.560±4.03 0.224±0.12 0.052±0.03 0.006±0.00 0.020±0.01 0.004±0.00 0.007±0.00 0.014±0.01 0.109±0.05 0.040±0.02 0.272±0.11

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001CT CIL_0001CT_0003 CGP 16:96467606-97170752
CIL_0001CW CIL_0001CW_0003 CGP 16:96592079-97439012

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005515 IPI protein binding
GO:0005886 IDA plasma membrane
GO:0007155 IEA cell adhesion
GO:0007162 IMP negative regulation of cell adhesion
GO:0007626 IMP locomotory behavior
GO:0016021 IEA integral component of membrane
GO:0030424 IDA axon
GO:0030426 IDA growth cone
GO:0042327 ISS positive regulation of phosphorylation
GO:0048813 IMP dendrite morphogenesis
GO:0048842 IDA positive regulation of axon extension involved in axon guidance
GO:0060060 IMP post-embryonic retina morphogenesis in camera-type eye
GO:0070593 IMP dendrite self-avoidance

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000024865 dscama Down syndrome cell adhesion molecule a protein_coding Danio_rerio
ENSDARG00000028118 dscamb Down syndrome cell adhesion molecule b protein_coding Danio_rerio
ENSG00000171587 DSCAM Down syndrome cell adhesion molecule protein_coding Homo_sapiens

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