C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: RGD motif, leucine rich repeats, tropomodulin domain and proline-rich containing
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000050357 Rltpr 10090 + 8:105690906-105698178 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000062574 Rltpr-201 105690906-105698178 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaENSMUST00000062574
Transcript ID Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta
ENSMUST00000062574 3.903±0.09 4.912±1.31 1.292±0.09 0.525±0.00 0.996±0.01 1.040±0.16 1.519±0.12 1.323±0.00 0.528±0.00 1.059±0.51

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006LW CIL_0006LW_0003 CGP 8:105636568-105698178
CIL_0005A9 CIL_0005A9_0002 CGP 8:105690906-105701095

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001772 IDA immunological synapse
GO:0005515 IPI protein binding
GO:0005737 IDA cytoplasm
GO:0005911 IDA cell-cell junction
GO:0008290 IDA F-actin capping protein complex
GO:0016020 IEA membrane
GO:0016477 IEA cell migration
GO:0030011 IEA maintenance of cell polarity
GO:0032729 IMP positive regulation of interferon-gamma production
GO:0042102 IMP positive regulation of T cell proliferation
GO:0045184 IMP establishment of protein localization
GO:0045591 IMP positive regulation of regulatory T cell differentiation
GO:0048538 IMP thymus development
GO:0048872 IMP homeostasis of number of cells
GO:0050852 IMP T cell receptor signaling pathway
GO:1900042 IMP positive regulation of interleukin-2 secretion
GO:1902715 IMP positive regulation of interferon-gamma secretion

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000056639 RLTPR RGD motif, leucine rich repeats, tropomodulin domain and proline-rich containing protein_coding Danio_rerio
ENSG00000159753 RLTPR RGD motif, leucine rich repeats, tropomodulin domain and proline-rich containing protein_coding Homo_sapiens

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