C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: microtubule crosslinking factor 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000052105 Mtcl1 10090 - 17:66336982-66449750 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000086693 Mtcl1-001 66336982-66449750 protein_coding
  ENSMUST00000097291 Mtcl1-002 66336986-66449750 protein_coding
  ENSMUST00000127259 Mtcl1-005 66385746-66448369 retained_intron
  ENSMUST00000129525 Mtcl1-010 66343946-66346545 retained_intron
  ENSMUST00000129841 Mtcl1-008 66366344-66374664 processed_transcript
  ENSMUST00000134139 Mtcl1-004 66347966-66378931 retained_intron
  ENSMUST00000142154 Mtcl1-007 66358041-66378058 retained_intron
  ENSMUST00000143420 Mtcl1-009 66354205-66362726 processed_transcript
  ENSMUST00000144492 Mtcl1-006 66354370-66378444 processed_transcript
  ENSMUST00000145347 Mtcl1-003 66336988-66385910 protein_coding
  ENSMUST00000177034 Mtcl1-011 66337678-66439032 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000086693ENSMUST00000097291ENSMUST00000127259ENSMUST00000129525ENSMUST00000134139ENSMUST00000142154ENSMUST00000143420ENSMUST00000145347ENSMUST00000177034
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000086693 0.400±0.15 1.014±0.35 0.871±0.29 1.810±0.00 0.478±0.27 0.638±0.08 0.291±0.14 0.466±0.13 0.014±0.00 8.134±4.12 0.466±0.08 3.615±2.14 1.091±1.24 1.454±0.58
ENSMUST00000097291 N/A N/A N/A 3.061±0.00 N/A 0.300±0.00 N/A N/A 0.002±0.00 N/A N/A N/A N/A N/A
ENSMUST00000127259 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 2.664±0.00 13.124±0.00
ENSMUST00000129525 N/A N/A N/A N/A N/A N/A N/A N/A 0.147±0.00 N/A N/A N/A N/A N/A
ENSMUST00000134139 N/A N/A N/A N/A 0.243±0.00 N/A N/A N/A 0.024±0.01 N/A N/A N/A 0.244±0.00 N/A
ENSMUST00000142154 N/A N/A N/A N/A N/A N/A N/A N/A 0.127±0.07 N/A N/A N/A N/A N/A
ENSMUST00000143420 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 37.203±0.00
ENSMUST00000145347 0.147±0.07 N/A 0.921±0.00 1.765±0.00 0.181±0.00 0.628±0.00 0.160±0.00 0.386±0.05 0.021±0.01 3.764±0.00 0.360±0.09 1.170±0.00 1.913±1.01 1.083±0.09
ENSMUST00000177034 N/A N/A N/A N/A N/A N/A 0.084±0.00 N/A 0.004±0.00 N/A N/A 1.108±0.00 N/A 1.452±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000922 IDA spindle pole
GO:0001578 IDA microtubule bundle formation
GO:0005515 IPI protein binding
GO:0005615 IEA extracellular space
GO:0005737 IEA cytoplasm
GO:0005856 IDA cytoskeleton
GO:0005886 IEA plasma membrane
GO:0008017 IDA microtubule binding
GO:0010506 IEA regulation of autophagy
GO:0016327 IDA apicolateral plasma membrane
GO:0016328 IDA lateral plasma membrane
GO:0030496 IDA midbody
GO:0042803 IDA protein homodimerization activity
GO:0044822 IEA poly(A) RNA binding
GO:0045197 IDA establishment or maintenance of epithelial cell apical/basal polarity
GO:0090314 IDA positive regulation of protein targeting to membrane
GO:0097427 IDA microtubule bundle
GO:2000576 IDA positive regulation of microtubule motor activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000091408 MTCL1 (2 of 2) microtubule crosslinking factor 1 protein_coding Danio_rerio
ENSG00000168502 MTCL1 microtubule crosslinking factor 1 protein_coding Homo_sapiens

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