C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: jun proto-oncogene
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000052684 Jun 10090 - 4:95049034-95052222 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000107094 Jun-001 95049034-95052222 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000107094
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000107094 26.986±6.90 110.725±19.07 19.022±3.64 18.733±3.26 22.266±9.72 59.907±5.69 12.175±2.77 9.454±0.79 2.875±1.37 114.134±25.29 18.366±2.78 58.493±18.06 25.887±8.21 2.696±0.50

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001N6 CIL_0001N6_0002 CGP 4:94942040-95052222
CIL_0008Y5 CIL_0008Y5_0002 VISTA 4:95017404-95619020
CIL_0007ZB CIL_0007ZB_0002 VISTA 4:95017529-95618734
CIL_0001N7 CIL_0001N7_0002 CGP 4:95049034-95926939

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000790 IEA nuclear chromatin
GO:0000980 IEA RNA polymerase II distal enhancer sequence-specific DNA binding
GO:0001077 IEA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001102 IEA RNA polymerase II activating transcription factor binding
GO:0001525 IMP angiogenesis
GO:0001774 IMP microglial cell activation
GO:0001836 IEA release of cytochrome c from mitochondria
GO:0001889 IMP liver development
GO:0001938 IMP positive regulation of endothelial cell proliferation
GO:0003151 IMP outflow tract morphogenesis
GO:0003677 IDA DNA binding
GO:0003690 IEA double-stranded DNA binding
GO:0003713 IEA transcription coactivator activity
GO:0005100 IEA Rho GTPase activator activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005667 IDA transcription factor complex
GO:0005719 IEA nuclear euchromatin
GO:0005829 IEA cytosol
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IMP regulation of transcription, DNA-templated
GO:0006366 IEA transcription from RNA polymerase II promoter
GO:0007179 IEA transforming growth factor beta receptor signaling pathway
GO:0007184 IEA SMAD protein import into nucleus
GO:0007568 IEA aging
GO:0007612 IEA learning
GO:0007623 IEA circadian rhythm
GO:0008134 IEA transcription factor binding
GO:0008284 IEA positive regulation of cell proliferation
GO:0008285 IGI negative regulation of cell proliferation
GO:0009314 IEA response to radiation
GO:0009612 IEA response to mechanical stimulus
GO:0009987 IMP cellular process
GO:0010033 IEA response to organic substance
GO:0014070 IEA response to organic cyclic compound
GO:0017053 IPI transcriptional repressor complex
GO:0019899 IEA enzyme binding
GO:0030224 IMP monocyte differentiation
GO:0031103 IMP axon regeneration
GO:0031953 IMP negative regulation of protein autophosphorylation
GO:0032321 IEA positive regulation of Rho GTPase activity
GO:0032496 IEA response to lipopolysaccharide
GO:0034097 IEA response to cytokine
GO:0035026 IMP leading edge cell differentiation
GO:0035497 IEA cAMP response element binding
GO:0042493 IDA response to drug
GO:0042542 IEA response to hydrogen peroxide
GO:0043065 IEA positive regulation of apoptotic process
GO:0043066 IMP negative regulation of apoptotic process
GO:0043392 IEA negative regulation of DNA binding
GO:0043524 IMP negative regulation of neuron apoptotic process
GO:0043525 IEA positive regulation of neuron apoptotic process
GO:0043922 IEA negative regulation by host of viral transcription
GO:0043923 IEA positive regulation by host of viral transcription
GO:0044212 IDA transcription regulatory region DNA binding
GO:0044822 IEA poly(A) RNA binding
GO:0045657 IEA positive regulation of monocyte differentiation
GO:0045740 IEA positive regulation of DNA replication
GO:0045892 IEA negative regulation of transcription, DNA-templated
GO:0045893 IEA positive regulation of transcription, DNA-templated
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0048146 IDA positive regulation of fibroblast proliferation
GO:0048661 IEA positive regulation of smooth muscle cell proliferation
GO:0051365 IEA cellular response to potassium ion starvation
GO:0051591 IEA response to cAMP
GO:0051726 IMP regulation of cell cycle
GO:0051899 IEA membrane depolarization
GO:0060395 IEA SMAD protein signal transduction
GO:0070412 IEA R-SMAD binding
GO:0071277 IDA cellular response to calcium ion
GO:0071837 IEA HMG box domain binding
GO:1990441 IEA negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000043531 jun jun proto-oncogene protein_coding Danio_rerio
ENSG00000177606 JUN jun proto-oncogene protein_coding Homo_sapiens

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