C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: protein kinase, cGMP-dependent, type I
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000052920 Prkg1 10090 - 19:30567551-31765033 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000065067 Prkg1-001 30567551-31765033 protein_coding
  ENSMUST00000073581 Prkg1-002 30568547-31664370 protein_coding
  ENSMUST00000182401 Prkg1-004 30708885-30781452 retained_intron
  ENSMUST00000182459 Prkg1-005 30568963-30574155 processed_transcript
  ENSMUST00000182527 Prkg1-007 30619371-30625491 processed_transcript
  ENSMUST00000182685 Prkg1-003 31742114-31764973 protein_coding
  ENSMUST00000183135 Prkg1-006 30568961-30574155 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000065067ENSMUST00000073581ENSMUST00000182459ENSMUST00000182527ENSMUST00000182685ENSMUST00000183135
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000065067 0.298±0.17 0.285±0.00 N/A 0.290±0.15 N/A 0.104±0.00 0.322±0.19 0.076±0.03 0.539±0.00 0.554±0.00 0.584±0.10 0.251±0.10 0.840±0.30
ENSMUST00000073581 1.189±0.89 N/A 1.444±0.00 0.666±0.17 0.814±0.25 0.744±0.13 0.444±0.11 0.066±0.06 1.970±0.16 N/A 1.202±0.78 0.299±0.21 N/A
ENSMUST00000182459 N/A N/A N/A 2.011±0.00 N/A 1.455±0.00 0.826±0.08 N/A N/A N/A N/A N/A 17.515±3.48
ENSMUST00000182527 N/A N/A N/A 0.499±0.06 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000182685 N/A N/A N/A N/A N/A N/A N/A 0.095±0.00 N/A N/A N/A N/A N/A
ENSMUST00000183135 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 20.245±6.49

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000ID CIL_0000ID_0002 CGP 19:30567551-31765033

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001764 IMP neuron migration
GO:0004672 IDA protein kinase activity
GO:0004692 IDA cGMP-dependent protein kinase activity
GO:0005246 ISS calcium channel regulator activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005737 ISS cytoplasm
GO:0005794 IDA Golgi apparatus
GO:0005886 IDA plasma membrane
GO:0006468 IDA protein phosphorylation
GO:0007165 IDA signal transduction
GO:0016358 IMP dendrite development
GO:0019934 IMP cGMP-mediated signaling
GO:0030553 IDA cGMP binding
GO:0030900 IMP forebrain development
GO:0043087 ISS regulation of GTPase activity
GO:0045986 IMP negative regulation of smooth muscle contraction
GO:0060087 IMP relaxation of vascular smooth muscle
GO:0090331 ISS negative regulation of platelet aggregation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000020656 prkg1a protein kinase, cGMP-dependent, type Ia protein_coding Danio_rerio
ENSDARG00000031702 prkg1b protein kinase, cGMP-dependent, type Ib protein_coding Danio_rerio
ENSG00000185532 PRKG1 protein kinase, cGMP-dependent, type I protein_coding Homo_sapiens

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