C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: protein kinase, cGMP-dependent, type I
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000073581 Prkg1-002 ENSMUSG00000052920 10090 - 19:30568547-31664370 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBrainBreastColonHeartKidneyLiverLungOvaryPlacentaENSMUST00000073581
Transcript ID Adipose Brain Breast Colon Heart Kidney Liver Lung Ovary Placenta
ENSMUST00000073581 1.189±0.89 1.444±0.00 0.666±0.17 0.814±0.25 0.744±0.13 0.444±0.11 0.066±0.06 1.970±0.16 1.202±0.78 0.299±0.21

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000ID CIL_0000ID_0002 CGP 19:30567551-31765033

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001764 IMP neuron migration
GO:0004672 IDA protein kinase activity
GO:0004692 IDA cGMP-dependent protein kinase activity
GO:0005246 ISS calcium channel regulator activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005737 ISS cytoplasm
GO:0005794 IDA Golgi apparatus
GO:0005886 IDA plasma membrane
GO:0006468 IDA protein phosphorylation
GO:0007165 IDA signal transduction
GO:0016358 IMP dendrite development
GO:0019934 IMP cGMP-mediated signaling
GO:0030553 IDA cGMP binding
GO:0030900 IMP forebrain development
GO:0043087 ISS regulation of GTPase activity
GO:0045986 IMP negative regulation of smooth muscle contraction
GO:0060087 IMP relaxation of vascular smooth muscle
GO:0090331 ISS negative regulation of platelet aggregation

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000373975 PRKG1-005 protein_coding Homo_sapiens 0 2121
ENST00000373976 PRKG1-004 protein_coding Homo_sapiens 0 713
ENST00000373980 PRKG1-002 protein_coding Homo_sapiens 0 3901
ENST00000373985 PRKG1-001 protein_coding Homo_sapiens 0 3256
ENST00000401604 PRKG1-201 protein_coding Homo_sapiens 0 2876

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