C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: DIS3 mitotic control homolog (S. cerevisiae)-like 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000053333 Dis3l2 10090 + 1:86703808-87050095 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000065694 Dis3l2-002 86703843-87050092 protein_coding
  ENSMUST00000168237 Dis3l2-001 86703819-87050095 protein_coding
  ENSMUST00000186682 Dis3l2-006 86857371-86858105 retained_intron
  ENSMUST00000188121 Dis3l2-004 86703808-86748331 processed_transcript
  ENSMUST00000189044 Dis3l2-005 86703828-86882439 retained_intron
  ENSMUST00000190618 Dis3l2-003 86703828-87049195 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000065694ENSMUST00000168237ENSMUST00000190618
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000065694 4.265±1.76 6.364±1.25 4.492±0.83 6.106±3.58 2.517±0.72 3.857±0.44 1.411±0.82 5.624±1.49 3.607±1.01 4.653±0.84 0.853±0.21 4.932±2.38 2.711±1.24 10.466±3.22
ENSMUST00000168237 1.624±0.43 1.359±0.39 1.897±0.13 5.428±1.93 2.638±1.80 0.946±0.00 1.700±0.20 2.488±0.41 1.137±0.22 2.245±0.42 3.179±0.18 6.058±3.09 1.210±0.43 4.222±0.87
ENSMUST00000190618 N/A N/A N/A N/A 1.235±0.36 0.645±0.00 N/A N/A N/A 0.985±0.00 N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000899 CIL_000899_0002 VISTA 1:86187174-86788752
CIL_0007WD CIL_0007WD_0002 VISTA 1:86187834-86792789
CIL_0007FN CIL_0007FN_0002 CGP 1:86666291-87050095
CIL_0007FQ CIL_0007FQ_0002 CGP 1:86703808-87089928

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000175 IDA 3'-5'-exoribonuclease activity
GO:0000287 IDA magnesium ion binding
GO:0000291 ISS nuclear-transcribed mRNA catabolic process, exonucleolytic
GO:0000932 ISS cytoplasmic mRNA processing body
GO:0004540 ISS ribonuclease activity
GO:0005515 IEA protein binding
GO:0005737 ISS cytoplasm
GO:0007067 ISS mitotic nuclear division
GO:0008266 IDA poly(U) RNA binding
GO:0008285 ISS negative regulation of cell proliferation
GO:0010587 IMP miRNA catabolic process
GO:0019827 IMP stem cell maintenance
GO:0034427 IEA nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'
GO:0051306 ISS mitotic sister chromatid separation
GO:0090501 IEA RNA phosphodiester bond hydrolysis
GO:0090503 IEA RNA phosphodiester bond hydrolysis, exonucleolytic
GO:1990074 ISS polyuridylation-dependent mRNA catabolic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000033259 dis3l2 DIS3 mitotic control homolog (S. cerevisiae)-like 2 protein_coding Danio_rerio
ENSG00000144535 DIS3L2 DIS3 like 3'-5' exoribonuclease 2 protein_coding Homo_sapiens

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