C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: DIS3 mitotic control homolog (S. cerevisiae)-like 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000168237 Dis3l2-001 ENSMUSG00000053333 10090 + 1:86703819-87050095 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000168237
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000168237 1.624±0.43 1.359±0.39 1.897±0.13 5.428±1.93 2.638±1.80 0.946±0.00 1.700±0.20 2.488±0.41 1.137±0.22 2.245±0.42 3.179±0.18 6.058±3.09 1.210±0.43 4.222±0.87

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000899 CIL_000899_0002 VISTA 1:86187174-86788752
CIL_0007WD CIL_0007WD_0002 VISTA 1:86187834-86792789
CIL_0007FN CIL_0007FN_0002 CGP 1:86666291-87050095
CIL_0007FQ CIL_0007FQ_0002 CGP 1:86703808-87089928

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000175 IDA 3'-5'-exoribonuclease activity
GO:0000287 IDA magnesium ion binding
GO:0000291 ISS nuclear-transcribed mRNA catabolic process, exonucleolytic
GO:0000932 ISS cytoplasmic mRNA processing body
GO:0004540 ISS ribonuclease activity
GO:0005515 IEA protein binding
GO:0005737 ISS cytoplasm
GO:0007067 ISS mitotic nuclear division
GO:0008266 IDA poly(U) RNA binding
GO:0008285 ISS negative regulation of cell proliferation
GO:0010587 IMP miRNA catabolic process
GO:0019827 IMP stem cell maintenance
GO:0034427 IEA nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'
GO:0051306 ISS mitotic sister chromatid separation
GO:0090501 IEA RNA phosphodiester bond hydrolysis
GO:0090503 IEA RNA phosphodiester bond hydrolysis, exonucleolytic
GO:1990074 ISS polyuridylation-dependent mRNA catabolic process

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000273009 DIS3L2-001 protein_coding Homo_sapiens 0 1273
ENST00000325385 DIS3L2-201 protein_coding Homo_sapiens 0 2409
ENST00000390005 DIS3L2-002 nonsense_mediated_decay Homo_sapiens 0 1435
ENST00000409307 DIS3L2-015 protein_coding Homo_sapiens 0 2409
ENST00000409401 DIS3L2-003 protein_coding Homo_sapiens 0 599
ENST00000417808 DIS3L2-007 protein_coding Homo_sapiens 4e-31 139
ENST00000418143 DIS3L2-012 protein_coding Homo_sapiens 4e-31 139
ENST00000424049 DIS3L2-010 protein_coding Homo_sapiens 0 1238
ENST00000429283 DIS3L2-006 retained_intron Homo_sapiens 0 604
ENST00000433430 DIS3L2-005 nonsense_mediated_decay Homo_sapiens 0 599
ENST00000441279 DIS3L2-008 protein_coding Homo_sapiens 0 555
ENST00000445090 DIS3L2-004 nonsense_mediated_decay Homo_sapiens 0 869
ENST00000464554 DIS3L2-013 retained_intron Homo_sapiens 0 342
ENST00000470087 DIS3L2-009 processed_transcript Homo_sapiens 0 241
ENST00000509197 DIS3L2P1-001 unprocessed_pseudogene Homo_sapiens 0.0000000000006 79

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