C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: excision repair cross-complementing rodent repair deficiency, complementation group 6
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000054051 Ercc6 10090 + 14:32513521-32580989 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000066807 Ercc6-201 32513521-32580989 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000066807
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000066807 0.659±0.26 2.054±0.54 1.818±1.49 4.407±2.42 1.890±0.35 1.608±0.83 0.677±0.12 1.980±0.31 1.758±0.82 1.442±0.24 0.670±0.23 2.738±0.84 2.046±1.15 1.935±0.53

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00084A CIL_00084A_0002 VISTA 14:32298253-32899721
CIL_0008ZL CIL_0008ZL_0002 VISTA 14:32470674-33071522
CIL_00002R CIL_00002R_0002 CGP 14:32513521-32649246

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000303 IMP response to superoxide
GO:0003677 IEA DNA binding
GO:0003682 IEA chromatin binding
GO:0005515 IEA protein binding
GO:0005524 IEA ATP binding
GO:0005634 IEA nucleus
GO:0005654 IEA nucleoplasm
GO:0005730 IEA nucleolus
GO:0006200 IEA ATP catabolic process
GO:0006281 IMP DNA repair
GO:0006283 IMP transcription-coupled nucleotide-excision repair
GO:0006284 IEA base-excision repair
GO:0006290 IMP pyrimidine dimer repair
GO:0006362 IMP transcription elongation from RNA polymerase I promoter
GO:0006974 IMP cellular response to DNA damage stimulus
GO:0006979 IMP response to oxidative stress
GO:0007256 IMP activation of JNKK activity
GO:0007257 IMP activation of JUN kinase activity
GO:0008022 IEA protein C-terminus binding
GO:0008023 IEA transcription elongation factor complex
GO:0008094 IEA DNA-dependent ATPase activity
GO:0008630 IMP intrinsic apoptotic signaling pathway in response to DNA damage
GO:0009411 IMP response to UV
GO:0009636 IMP response to toxic substance
GO:0010165 IMP response to X-ray
GO:0010224 IMP response to UV-B
GO:0010332 IMP response to gamma radiation
GO:0030296 IEA protein tyrosine kinase activator activity
GO:0032403 IEA protein complex binding
GO:0032784 IEA regulation of DNA-templated transcription, elongation
GO:0032786 IEA positive regulation of DNA-templated transcription, elongation
GO:0035264 IGI multicellular organism growth
GO:0045494 IMP photoreceptor cell maintenance
GO:0047485 IEA protein N-terminus binding
GO:0061098 IEA positive regulation of protein tyrosine kinase activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000075612 ercc6 excision repair cross-complementing rodent repair deficiency, complementation group 6 protein_coding Danio_rerio
ENSG00000225830 ERCC6 excision repair cross-complementation group 6 protein_coding Homo_sapiens

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