C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: excision repair cross-complementation group 6
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000225830 ERCC6 9606 - 10:49455368-49539538 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000355832 ERCC6-001 49455368-49539026 protein_coding
  ENST00000462247 ERCC6-005 49530724-49539538 protein_coding
  ENST00000465653 ERCC6-002 49460024-49470281 processed_transcript
  ENST00000475116 ERCC6-003 49483368-49505999 processed_transcript
  ENST00000479652 ERCC6-004 49524936-49530737 processed_transcript
  ENST00000623073 ERCC6-009 49456655-49506480 nonsense_mediated_decay
  ENST00000623115 ERCC6-006 49458788-49502122 protein_coding
  ENST00000623318 ERCC6-007 49483386-49502157 protein_coding
  ENST00000623788 ERCC6-008 49500660-49506408 retained_intron
  ENST00000624341 ERCC6-010 49455368-49476258 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000355832ENST00000623073ENST00000623115ENST00000624341
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000355832 N/A 0.224±0.00 0.463±0.00 0.393±0.15 0.346±0.00 0.769±0.00 0.467±0.09 1.221±0.06 0.964±0.76 0.371±0.10 0.702±0.42 0.731±0.51 0.744±0.61 0.904±0.23
ENST00000623073 N/A 0.118±0.00 N/A N/A N/A N/A 0.163±0.00 0.238±0.00 N/A 0.818±0.00 N/A 0.709±0.00 N/A N/A
ENST00000623115 0.793±0.00 N/A N/A 0.471±0.00 0.739±0.31 0.623±0.09 N/A N/A N/A 0.893±0.00 N/A 0.736±0.18 0.358±0.00 2.361±0.10
ENST00000624341 N/A N/A N/A N/A N/A N/A N/A N/A 0.152±0.00 N/A 0.184±0.00 1.284±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008ZL CIL_0008ZL_0001 VISTA 10:48905403-49506260
CIL_00084A CIL_00084A_0001 VISTA 10:49095759-49697208
CIL_0007OS CIL_0007OS_0002 UCNEbase 10:49372114-49500701

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000303 IEA response to superoxide
GO:0003677 IDA:IEA DNA binding
GO:0003682 IDA chromatin binding
GO:0005515 IPI protein binding
GO:0005524 IDA:IEA ATP binding
GO:0005634 IDA nucleus
GO:0005654 IDA nucleoplasm
GO:0005730 IDA nucleolus
GO:0006200 IDA ATP catabolic process
GO:0006281 TAS DNA repair
GO:0006283 IMP transcription-coupled nucleotide-excision repair
GO:0006284 IMP base-excision repair
GO:0006289 TAS nucleotide-excision repair
GO:0006290 IEA pyrimidine dimer repair
GO:0006362 IEA transcription elongation from RNA polymerase I promoter
GO:0006366 NAS transcription from RNA polymerase II promoter
GO:0006974 IEA cellular response to DNA damage stimulus
GO:0006979 IDA response to oxidative stress
GO:0007256 IEA activation of JNKK activity
GO:0007257 IEA activation of JUN kinase activity
GO:0008022 IPI protein C-terminus binding
GO:0008023 IDA transcription elongation factor complex
GO:0008094 IDA DNA-dependent ATPase activity
GO:0008630 IEA intrinsic apoptotic signaling pathway in response to DNA damage
GO:0009411 IDA response to UV
GO:0009636 IEA response to toxic substance
GO:0010165 IEA response to X-ray
GO:0010224 IEA response to UV-B
GO:0010332 IEA response to gamma radiation
GO:0030296 IDA protein tyrosine kinase activator activity
GO:0032403 IDA protein complex binding
GO:0032784 IDA regulation of DNA-templated transcription, elongation
GO:0032786 IDA positive regulation of DNA-templated transcription, elongation
GO:0035264 IEA multicellular organism growth
GO:0045494 IEA photoreceptor cell maintenance
GO:0047485 IPI protein N-terminus binding
GO:0061098 IDA positive regulation of protein tyrosine kinase activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000075612 ercc6 excision repair cross-complementing rodent repair deficiency, complementation group 6 protein_coding Danio_rerio
ENSMUSG00000054051 Ercc6 excision repair cross-complementing rodent repair deficiency, complementation group 6 protein_coding Mus_musculus

Loading