C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000054477 Kcnn2 10090 + 18:45268860-45686024 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000066890 Kcnn2-201 45269005-45686024 protein_coding
  ENSMUST00000167895 Kcnn2-002 45560154-45675362 processed_transcript
  ENSMUST00000169783 Kcnn2-202 45560154-45685882 protein_coding
  ENSMUST00000183623 Kcnn2-005 45268860-45289824 processed_transcript
  ENSMUST00000183850 Kcnn2-001 45269005-45685883 protein_coding
  ENSMUST00000183897 Kcnn2-004 45559811-45593065 retained_intron
  ENSMUST00000184101 Kcnn2-003 45559469-45671249 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000066890ENSMUST00000167895ENSMUST00000169783ENSMUST00000183623ENSMUST00000183850ENSMUST00000183897ENSMUST00000184101
Transcript ID Adipose Adrenal Bladder Brain Breast Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000066890 N/A N/A N/A N/A 0.044±0.00 N/A 0.177±0.00 0.041±0.00 N/A 0.191±0.03 N/A N/A 0.034±0.00
ENSMUST00000167895 0.083±0.00 N/A N/A N/A 0.071±0.00 1.992±0.41 0.431±0.17 2.152±1.94 N/A 0.440±0.07 0.437±0.00 0.076±0.05 0.175±0.05
ENSMUST00000169783 N/A N/A N/A 15.999±0.00 0.105±0.00 N/A N/A 0.020±0.00 N/A 0.302±0.10 0.717±0.07 0.099±0.03 0.136±0.00
ENSMUST00000183623 0.030±0.00 N/A N/A N/A N/A N/A N/A N/A N/A 0.144±0.00 N/A 0.021±0.01 0.018±0.00
ENSMUST00000183850 0.157±0.10 N/A 2.214±0.57 1.830±0.53 N/A 0.869±0.21 0.182±0.05 0.379±0.44 N/A 0.387±0.14 0.251±0.03 0.042±0.03 0.020±0.00
ENSMUST00000183897 N/A N/A N/A N/A 0.057±0.03 N/A N/A 3.745±0.63 N/A N/A N/A N/A N/A
ENSMUST00000184101 0.053±0.00 68.778±4.66 N/A N/A 0.094±0.00 N/A 0.292±0.11 1.652±1.12 0.195±0.07 N/A 1.057±0.45 0.060±0.00 0.097±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004UP CIL_0004UP_0002 CGP 18:44828665-45686024
CIL_0004UO CIL_0004UO_0002 CGP 18:45268860-46212607

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005216 IDA ion channel activity
GO:0005516 IBA calmodulin binding
GO:0005790 IDA smooth endoplasmic reticulum
GO:0005886 IDA plasma membrane
GO:0006811 IDA ion transport
GO:0016021 IEA integral component of membrane
GO:0016286 IBA small conductance calcium-activated potassium channel activity
GO:0030018 IDA Z disc
GO:0030315 IDA T-tubule
GO:0042803 IEA protein homodimerization activity
GO:0043025 IBA neuronal cell body
GO:0043197 IDA dendritic spine
GO:0051393 IEA alpha-actinin binding
GO:0071805 IBA potassium ion transmembrane transport
GO:1901379 IEA regulation of potassium ion transmembrane transport

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000014939 KCNN2 potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2 protein_coding Danio_rerio
ENSG00000080709 KCNN2 potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2 protein_coding Homo_sapiens

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