C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: phospholipase A2 receptor 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000054580 Pla2r1 10090 - 2:60417543-60553308 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000067708 Pla2r1-201 60417543-60553308 protein_coding
  ENSMUST00000112525 Pla2r1-001 60417543-60553308 protein_coding
  ENSMUST00000126327 Pla2r1-006 60420025-60424307 processed_transcript
  ENSMUST00000128208 Pla2r1-002 60451109-60553308 processed_transcript
  ENSMUST00000134583 Pla2r1-005 60451992-60455254 processed_transcript
  ENSMUST00000136034 Pla2r1-004 60440890-60443424 processed_transcript
  ENSMUST00000150373 Pla2r1-003 60533878-60553308 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000067708ENSMUST00000128208
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000067708 1.361±0.45 0.328±0.12 9.477±1.80 0.086±0.01 0.727±0.26 0.669±0.24 0.212±0.07 1.266±0.20 0.153±0.09 1.653±0.59 0.308±0.10 1.639±0.86 1.136±0.37 0.284±0.12
ENSMUST00000128208 N/A 0.218±0.00 N/A 0.109±0.07 0.516±0.04 N/A 0.231±0.01 N/A 0.123±0.03 N/A 0.180±0.00 0.918±0.33 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005TY CIL_0005TY_0002 CGP 2:60292103-60553308
CIL_0005TX CIL_0005TX_0002 CGP 2:60417543-60722643

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001816 ISS cytokine production
GO:0004872 ISS receptor activity
GO:0005576 IEA extracellular region
GO:0005886 ISS plasma membrane
GO:0006898 IDA receptor-mediated endocytosis
GO:0016021 IEA integral component of membrane
GO:0030246 IEA carbohydrate binding
GO:0043235 ISO receptor complex
GO:0043274 IPI phospholipase binding
GO:0043517 ISS positive regulation of DNA damage response, signal transduction by p53 class mediator
GO:0072593 ISS reactive oxygen species metabolic process
GO:0090238 IDA positive regulation of arachidonic acid secretion
GO:0090399 ISS replicative senescence
GO:0090403 ISS oxidative stress-induced premature senescence
GO:1900138 IDA negative regulation of phospholipase A2 activity
GO:1900139 IDA negative regulation of arachidonic acid secretion

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000077474 PLA2R1 phospholipase A2 receptor 1, 180kDa protein_coding Danio_rerio
ENSG00000153246 PLA2R1 phospholipase A2 receptor 1, 180kDa protein_coding Homo_sapiens

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