C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: phospholipase A2 receptor 1, 180kDa
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000153246 PLA2R1 9606 - 2:159932006-160062610 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000283243 PLA2R1-001 159937851-160062610 protein_coding
  ENST00000392771 PLA2R1-002 159945815-160062610 protein_coding
  ENST00000460710 PLA2R1-003 159932006-159945000 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000283243ENST00000392771ENST00000460710
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000283243 0.663±0.00 0.615±0.00 2.501±0.00 0.152±0.03 1.406±0.28 0.501±0.00 0.104±0.05 3.753±0.00 0.066±0.00 0.446±0.15 0.065±0.03 0.659±0.11 0.284±0.06 0.410±0.25
ENST00000392771 0.511±0.00 0.324±0.00 1.357±0.00 0.075±0.01 0.812±0.10 0.710±0.09 0.172±0.04 3.505±0.00 2.358±0.00 0.493±0.28 0.151±0.00 1.256±0.63 0.569±0.35 0.305±0.21
ENST00000460710 N/A N/A N/A N/A N/A N/A N/A 0.939±0.00 N/A N/A N/A 4.849±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005TY CIL_0005TY_0001 CGP 2:159803355-160062610
CIL_0005TX CIL_0005TX_0001 CGP 2:159932006-160271888

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001816 IMP cytokine production
GO:0004872 IDA receptor activity
GO:0005576 ISS extracellular region
GO:0005886 IDA plasma membrane
GO:0005887 NAS integral component of plasma membrane
GO:0006898 IDA receptor-mediated endocytosis
GO:0009986 IDA cell surface
GO:0016021 IEA integral component of membrane
GO:0030246 IEA carbohydrate binding
GO:0043235 IDA receptor complex
GO:0043274 IPI phospholipase binding
GO:0043517 IMP positive regulation of DNA damage response, signal transduction by p53 class mediator
GO:0070062 IDA extracellular vesicular exosome
GO:0072593 IDA reactive oxygen species metabolic process
GO:0090238 ISS positive regulation of arachidonic acid secretion
GO:0090399 IMP replicative senescence
GO:0090403 IMP oxidative stress-induced premature senescence
GO:1900138 ISS negative regulation of phospholipase A2 activity
GO:1900139 ISS negative regulation of arachidonic acid secretion

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000077474 PLA2R1 phospholipase A2 receptor 1, 180kDa protein_coding Danio_rerio
ENSMUSG00000054580 Pla2r1 phospholipase A2 receptor 1 protein_coding Mus_musculus

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