C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: glypican 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000055653 Gpc3 10090 - X:52272426-52613950 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000069360 Gpc3-001 52272426-52613921 protein_coding
  ENSMUST00000114857 Gpc3-002 52387664-52613950 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000069360ENSMUST00000114857
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000069360 14.248±3.10 7.245±1.83 24.570±3.30 11.644±7.78 19.724±8.03 2.132±0.69 6.111±1.83 12.460±2.11 105.081±108.71 43.150±13.50 1.935±0.30 13.970±9.15 90.639±92.82 0.496±0.21
ENSMUST00000114857 10.066±5.12 35.140±5.05 N/A 3.662±0.26 36.574±24.46 7.510±1.48 2.002±0.65 6.452±3.98 7.153±15.24 78.712±20.75 N/A 45.251±7.11 N/A 0.389±0.14

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000GF CIL_0000GF_0003 CGP X:52053021-52613950
CIL_0000SR CIL_0000SR_0002 CGP X:52272426-52799468

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001658 IGI branching involved in ureteric bud morphogenesis
GO:0001822 IMP kidney development
GO:0005515 IPI protein binding
GO:0005578 IEA proteinaceous extracellular matrix
GO:0005764 IDA lysosome
GO:0005796 TAS Golgi lumen
GO:0005886 IDA plasma membrane
GO:0005887 ISS integral component of plasma membrane
GO:0008285 IGI negative regulation of cell proliferation
GO:0009887 IMP organ morphogenesis
GO:0009948 IGI anterior/posterior axis specification
GO:0010171 IMP body morphogenesis
GO:0010466 IEA negative regulation of peptidase activity
GO:0030282 IMP bone mineralization
GO:0030316 IMP osteoclast differentiation
GO:0030324 IMP lung development
GO:0030513 IMP positive regulation of BMP signaling pathway
GO:0035116 IGI embryonic hindlimb morphogenesis
GO:0040008 IMP regulation of growth
GO:0043395 IEA heparan sulfate proteoglycan binding
GO:0045732 IDA positive regulation of protein catabolic process
GO:0045807 IDA positive regulation of endocytosis
GO:0045879 IMP negative regulation of smoothened signaling pathway
GO:0045880 IMP positive regulation of smoothened signaling pathway
GO:0045926 IMP negative regulation of growth
GO:0046326 IDA positive regulation of glucose import
GO:0046658 IMP anchored component of plasma membrane
GO:0050680 IMP negative regulation of epithelial cell proliferation
GO:0060422 ISS peptidyl-dipeptidase inhibitor activity
GO:0060976 IMP coronary vasculature development
GO:0070062 IEA extracellular vesicular exosome
GO:0072111 IMP cell proliferation involved in kidney development
GO:0072138 IMP mesenchymal cell proliferation involved in ureteric bud development
GO:0072180 IMP mesonephric duct morphogenesis
GO:0072203 IMP cell proliferation involved in metanephros development
GO:0090090 IMP negative regulation of canonical Wnt signaling pathway
GO:2000096 IMP positive regulation of Wnt signaling pathway, planar cell polarity pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000032199 gpc3 glypican 3 protein_coding Danio_rerio
ENSG00000147257 GPC3 glypican 3 protein_coding Homo_sapiens

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