C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: glypican 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000147257 GPC3 9606 - X:133535745-133985895 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000370818 GPC3-001 133535745-133985895 protein_coding
  ENST00000394299 GPC3-201 133535754-133985646 protein_coding
  ENST00000406757 GPC3-002 133596366-133753702 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000370818ENST00000394299ENST00000406757
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000370818 48.222±0.00 5.749±0.00 7.306±0.00 0.343±0.07 21.488±12.54 12.048±10.96 2.160±1.38 15.130±15.00 2.201±1.89 52.009±42.40 1.992±0.00 9.311±8.63 207.368±14.84 3.766±1.41
ENST00000394299 N/A N/A N/A N/A N/A 0.568±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000406757 17.265±0.00 3.619±0.00 N/A N/A 8.593±5.93 6.977±0.00 0.421±0.00 0.316±0.00 N/A 3.349±0.00 0.225±0.00 10.303±10.08 158.969±0.00 2.191±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000GF CIL_0000GF_0002 CGP X:133300103-133985895
CIL_0000SR CIL_0000SR_0001 CGP X:133535745-134246207

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001523 TAS retinoid metabolic process
GO:0001658 IEA branching involved in ureteric bud morphogenesis
GO:0001822 IEA kidney development
GO:0005515 IPI protein binding
GO:0005578 IEA proteinaceous extracellular matrix
GO:0005764 IEA lysosome
GO:0005796 TAS Golgi lumen
GO:0005886 TAS plasma membrane
GO:0005887 TAS integral component of plasma membrane
GO:0005975 TAS carbohydrate metabolic process
GO:0006024 TAS glycosaminoglycan biosynthetic process
GO:0006027 TAS glycosaminoglycan catabolic process
GO:0007603 TAS phototransduction, visible light
GO:0008285 IEA negative regulation of cell proliferation
GO:0009653 TAS anatomical structure morphogenesis
GO:0009887 IEA organ morphogenesis
GO:0009948 IEA anterior/posterior axis specification
GO:0010171 IEA body morphogenesis
GO:0010466 IEA negative regulation of peptidase activity
GO:0016020 IEA membrane
GO:0030203 TAS glycosaminoglycan metabolic process
GO:0030204 TAS chondroitin sulfate metabolic process
GO:0030282 IEA bone mineralization
GO:0030316 IEA osteoclast differentiation
GO:0030324 IEA lung development
GO:0030513 IEA positive regulation of BMP signaling pathway
GO:0035116 IEA embryonic hindlimb morphogenesis
GO:0040008 IEA regulation of growth
GO:0043202 TAS lysosomal lumen
GO:0043395 IEA heparan sulfate proteoglycan binding
GO:0044281 TAS small molecule metabolic process
GO:0045732 IEA positive regulation of protein catabolic process
GO:0045807 IEA positive regulation of endocytosis
GO:0045879 IEA negative regulation of smoothened signaling pathway
GO:0045880 IEA positive regulation of smoothened signaling pathway
GO:0045926 IEA negative regulation of growth
GO:0046326 IEA positive regulation of glucose import
GO:0046658 IEA anchored component of plasma membrane
GO:0050680 IEA negative regulation of epithelial cell proliferation
GO:0060422 IDA peptidyl-dipeptidase inhibitor activity
GO:0060976 IEA coronary vasculature development
GO:0070062 IDA extracellular vesicular exosome
GO:0072111 IEA cell proliferation involved in kidney development
GO:0072138 ISS mesenchymal cell proliferation involved in ureteric bud development
GO:0072180 IEA mesonephric duct morphogenesis
GO:0072203 IEA cell proliferation involved in metanephros development
GO:0090090 IEA negative regulation of canonical Wnt signaling pathway
GO:2000096 IEA positive regulation of Wnt signaling pathway, planar cell polarity pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000032199 gpc3 glypican 3 protein_coding Danio_rerio
ENSMUSG00000055653 Gpc3 glypican 3 protein_coding Mus_musculus

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