C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: transcription factor 7 like 1 (T cell specific, HMG box)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000055799 Tcf7l1 10090 - 6:72626378-72789254 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000069536 Tcf7l1-001 72626378-72789254 protein_coding
  ENSMUST00000114053 Tcf7l1-003 72627272-72788952 protein_coding
  ENSMUST00000141743 Tcf7l1-002 72627591-72630270 processed_transcript
  ENSMUST00000149446 Tcf7l1-006 72632976-72788598 protein_coding
  ENSMUST00000182651 Tcf7l1-005 72648815-72671404 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000069536ENSMUST00000114053ENSMUST00000149446
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000069536 6.082±1.18 2.675±0.61 8.376±1.38 2.416±1.55 4.227±1.25 6.815±2.04 2.073±0.69 2.344±0.34 0.925±0.43 3.820±0.89 1.310±0.34 4.849±1.83 5.783±3.63 0.376±0.09
ENSMUST00000114053 3.833±1.61 1.799±0.41 3.103±1.02 1.289±0.25 4.226±0.84 N/A N/A 2.086±0.00 1.190±0.54 3.598±0.00 0.488±0.05 4.002±2.06 4.269±2.36 N/A
ENSMUST00000149446 N/A N/A N/A N/A 5.413±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0009AX CIL_0009AX_0002 VISTA 6:72353769-72955984

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003677 IDA DNA binding
GO:0003682 IDA chromatin binding
GO:0003700 IDA sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005667 IBA transcription factor complex
GO:0007420 IBA brain development
GO:0008013 IPI beta-catenin binding
GO:0008595 IMP anterior/posterior axis specification, embryo
GO:0035019 IGI somatic stem cell maintenance
GO:0043565 IBA sequence-specific DNA binding
GO:0043588 IGI skin development
GO:0044212 IBA transcription regulatory region DNA binding
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0046022 IDA positive regulation of transcription from RNA polymerase II promoter during mitosis
GO:0048319 IMP axial mesoderm morphogenesis
GO:0048699 IBA generation of neurons
GO:0048863 IMP stem cell differentiation
GO:0060070 IBA canonical Wnt signaling pathway
GO:2000036 IMP regulation of stem cell maintenance

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000007369 tcf7l1b transcription factor 7-like 1b (T-cell specific, HMG-box) protein_coding Danio_rerio
ENSDARG00000038159 tcf7l1a transcription factor 7-like 1a (T-cell specific, HMG-box) protein_coding Danio_rerio
ENSG00000152284 TCF7L1 transcription factor 7-like 1 (T-cell specific, HMG-box) protein_coding Homo_sapiens

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