C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: transcription factor 7 like 1 (T cell specific, HMG box)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000114053 Tcf7l1-003 ENSMUSG00000055799 10090 - 6:72627272-72788952 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastKidneyLiverLungMuscleOvaryPlacentaENSMUST00000114053
Transcript ID Adipose Adrenal Bladder Brain Breast Kidney Liver Lung Muscle Ovary Placenta
ENSMUST00000114053 3.833±1.61 1.799±0.41 3.103±1.02 1.289±0.25 4.226±0.84 2.086±0.00 1.190±0.54 3.598±0.00 0.488±0.05 4.002±2.06 4.269±2.36

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0009AX CIL_0009AX_0002 VISTA 6:72353769-72955984

Gene Ontology

GO IDEvidence TypeGO Description
GO:0003677 IDA DNA binding
GO:0003682 IDA chromatin binding
GO:0003700 IDA sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005667 IBA transcription factor complex
GO:0007420 IBA brain development
GO:0008013 IPI beta-catenin binding
GO:0008595 IMP anterior/posterior axis specification, embryo
GO:0035019 IGI somatic stem cell maintenance
GO:0043565 IBA sequence-specific DNA binding
GO:0043588 IGI skin development
GO:0044212 IBA transcription regulatory region DNA binding
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0046022 IDA positive regulation of transcription from RNA polymerase II promoter during mitosis
GO:0048319 IMP axial mesoderm morphogenesis
GO:0048699 IBA generation of neurons
GO:0048863 IMP stem cell differentiation
GO:0060070 IBA canonical Wnt signaling pathway
GO:2000036 IMP regulation of stem cell maintenance

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000282111 TCF7L1-001 protein_coding Homo_sapiens 0 1604
ENST00000442813 TCF7L1-004 protein_coding Homo_sapiens 2e-28 130
ENST00000490744 TCF7L1-003 retained_intron Homo_sapiens 0 274
ENST00000494519 TCF7L1-002 processed_transcript Homo_sapiens 4e-29 132

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