C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: tonsoku-like, DNA repair protein
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000059323 Tonsl 10090 - 15:76622088-76639958 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000078803 Tonsl-201 76622088-76626027 protein_coding
  ENSMUST00000163161 Tonsl-005 76637188-76638279 retained_intron
  ENSMUST00000163990 Tonsl-007 76626239-76629380 retained_intron
  ENSMUST00000165163 Tonsl-008 76626002-76629299 protein_coding
  ENSMUST00000165190 Tonsl-002 76632806-76639929 nonsense_mediated_decay
  ENSMUST00000166974 Tonsl-003 76638859-76639840 protein_coding
  ENSMUST00000168185 Tonsl-001 76626238-76639958 protein_coding
  ENSMUST00000168432 Tonsl-004 76638557-76639638 retained_intron
  ENSMUST00000171478 Tonsl-006 76632773-76633676 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000078803ENSMUST00000165190ENSMUST00000168185
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000078803 74.254±20.94 95.841±12.60 92.165±3.81 73.041±9.93 71.171±27.38 133.105±52.92 70.638±5.16 95.676±22.74 52.117±16.36 84.558±42.71 35.825±3.74 95.054±21.54 60.272±13.35 55.532±18.33
ENSMUST00000165190 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 2.055±0.00
ENSMUST00000168185 4.089±0.03 2.262±0.36 N/A 3.499±1.05 3.397±0.77 7.932±1.90 N/A N/A 5.557±3.10 N/A N/A 5.890±1.31 5.544±2.62 4.164±1.29

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007SS CIL_0007SS_0002 VISTA 15:76102685-76704351
CIL_00026P CIL_00026P_0002 CGP 15:76622088-76660117

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000724 IEA double-strand break repair via homologous recombination
GO:0000813 ISS ESCRT I complex
GO:0005634 IEA nucleus
GO:0005662 IEA DNA replication factor A complex
GO:0005737 ISS cytoplasm
GO:0005886 IEA plasma membrane
GO:0015031 IEA protein transport
GO:0031297 IEA replication fork processing
GO:0031397 ISS negative regulation of protein ubiquitination
GO:0035101 IEA FACT complex
GO:0042393 IEA histone binding
GO:0042555 IEA MCM complex
GO:0043162 ISS ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
GO:0043596 IEA nuclear replication fork

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000071294 TONSL tonsoku-like, DNA repair protein protein_coding Danio_rerio
ENSG00000160949 TONSL tonsoku-like, DNA repair protein protein_coding Homo_sapiens

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