C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: solute carrier family 9 (sodium/hydrogen exchanger), member 6
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000060681 Slc9a6 10090 + X:56609757-56664230 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000077741 Slc9a6-001 56609854-56664230 protein_coding
  ENSMUST00000114784 Slc9a6-002 56609856-56663841 protein_coding
  ENSMUST00000144068 Slc9a6-003 56609757-56633579 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000077741ENSMUST00000114784ENSMUST00000144068
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000077741 1.278±0.01 1.996±0.00 1.653±0.53 6.292±0.14 1.894±0.00 1.264±0.52 0.545±0.00 1.496±0.00 0.877±0.13 2.716±0.34 1.379±0.09 4.056±2.82 5.770±0.94 0.700±0.18
ENSMUST00000114784 9.374±0.64 4.850±0.74 3.838±0.11 13.473±3.93 5.992±0.51 3.648±0.89 2.560±1.28 5.716±1.28 2.008±0.69 7.938±1.55 3.253±1.48 4.846±1.55 7.365±2.79 1.089±0.54
ENSMUST00000144068 8.696±1.08 15.353±4.92 N/A N/A 12.530±5.06 9.115±1.40 2.547±0.52 6.883±2.18 3.649±0.54 11.106±3.14 N/A 5.623±1.13 9.682±0.00 1.177±0.13

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000GK CIL_0000GK_0003 CGP X:56585512-56664230
CIL_0000PQ CIL_0000PQ_0004 CGP X:56609757-56793346

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003674 ND molecular_function
GO:0005739 IDA mitochondrion
GO:0005768 IDA endosome
GO:0005769 IDA early endosome
GO:0005770 IDA late endosome
GO:0005789 IEA endoplasmic reticulum membrane
GO:0005886 IDA plasma membrane
GO:0006885 IEA regulation of pH
GO:0015385 IEA sodium:proton antiporter activity
GO:0015992 IMP proton transport
GO:0016021 IEA integral component of membrane
GO:0030425 IDA dendrite
GO:0031410 IDA cytoplasmic vesicle
GO:0031547 IMP brain-derived neurotrophic factor receptor signaling pathway
GO:0031901 IEA early endosome membrane
GO:0035725 IEA sodium ion transmembrane transport
GO:0043679 IDA axon terminus
GO:0044308 IDA axonal spine
GO:0045202 IDA synapse
GO:0048675 ISO axon extension
GO:0048812 ISO neuron projection morphogenesis
GO:0050808 IMP synapse organization
GO:0051386 IMP regulation of neurotrophin TRK receptor signaling pathway
GO:0055037 IDA recycling endosome
GO:0055038 IEA recycling endosome membrane
GO:0060996 IMP dendritic spine development
GO:0097484 ISO dendrite extension
GO:1902600 IEA hydrogen ion transmembrane transport

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000009209 slc9a6a solute carrier family 9 (sodium/hydrogen exchanger), member 6a protein_coding Danio_rerio
ENSDARG00000075382 slc9a6b solute carrier family 9 (sodium/hydrogen exchanger), member 6b protein_coding Danio_rerio
ENSG00000198689 SLC9A6 solute carrier family 9, subfamily A (NHE6, cation proton antiporter 6), member 6 protein_coding Homo_sapiens

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