C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: solute carrier family 9, subfamily A (NHE6, cation proton antiporter 6), member 6
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000198689 SLC9A6 9606 + X:135985439-136047264 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000370695 SLC9A6-002 135985468-136047264 protein_coding
  ENST00000370698 SLC9A6-001 135985468-136047264 protein_coding
  ENST00000370701 SLC9A6-003 135985439-136047139 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000370695ENST00000370698ENST00000370701
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000370695 N/A N/A N/A 9.782±0.00 N/A 1.925±0.00 N/A N/A 1.097±0.00 N/A N/A 0.635±0.12 N/A N/A
ENST00000370698 N/A 3.727±0.00 1.414±0.00 8.193±0.00 1.564±0.00 1.809±0.00 0.917±0.00 0.665±0.00 N/A 3.194±0.00 N/A 1.260±0.33 0.896±0.00 1.562±0.67
ENST00000370701 2.726±0.00 N/A N/A 12.844±6.00 2.462±0.32 2.438±0.00 2.888±1.33 2.405±1.05 0.951±0.00 0.530±0.00 3.015±2.31 2.116±1.06 0.889±0.22 1.893±0.55

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000GK CIL_0000GK_0002 CGP X:135962070-136047264
CIL_0000PQ CIL_0000PQ_0003 CGP X:135985439-136211359

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005739 IEA mitochondrion
GO:0005768 IEA endosome
GO:0005769 IEA early endosome
GO:0005770 IEA late endosome
GO:0005789 IDA endoplasmic reticulum membrane
GO:0005886 IDA plasma membrane
GO:0006810 TAS transport
GO:0006811 TAS ion transport
GO:0006812 IEA cation transport
GO:0006814 IEA sodium ion transport
GO:0006885 IEA regulation of pH
GO:0015299 IEA solute:proton antiporter activity
GO:0015385 IEA sodium:proton antiporter activity
GO:0015992 IEA proton transport
GO:0016021 IEA integral component of membrane
GO:0030425 IEA dendrite
GO:0031410 IEA cytoplasmic vesicle
GO:0031547 IEA brain-derived neurotrophic factor receptor signaling pathway
GO:0031901 IDA early endosome membrane
GO:0035725 IEA sodium ion transmembrane transport
GO:0043679 IEA axon terminus
GO:0044308 IEA axonal spine
GO:0045202 IEA synapse
GO:0048675 IDA axon extension
GO:0048812 IDA neuron projection morphogenesis
GO:0050808 IEA synapse organization
GO:0051386 IEA regulation of neurotrophin TRK receptor signaling pathway
GO:0055037 IEA recycling endosome
GO:0055038 IDA recycling endosome membrane
GO:0055085 TAS:IEA transmembrane transport
GO:0060996 IEA dendritic spine development
GO:0097484 IDA dendrite extension
GO:1902600 IEA hydrogen ion transmembrane transport

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000009209 slc9a6a solute carrier family 9 (sodium/hydrogen exchanger), member 6a protein_coding Danio_rerio
ENSDARG00000075382 slc9a6b solute carrier family 9 (sodium/hydrogen exchanger), member 6b protein_coding Danio_rerio
ENSMUSG00000060681 Slc9a6 solute carrier family 9 (sodium/hydrogen exchanger), member 6 protein_coding Mus_musculus

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