C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: brachyury
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000074667 T-001 ENSMUSG00000062327 10090 + 17:8434423-8442496 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBrainBreastHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000074667
Transcript ID Adipose Bladder Brain Breast Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000074667 0.036±0.00 0.007±0.00 0.182±0.08 0.027±0.01 0.019±0.00 0.013±0.00 0.016±0.01 0.044±0.02 0.024±0.00 0.158±0.13 0.017±0.01 0.065±0.04

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0000785 IMP chromatin
GO:0000790 IEA nuclear chromatin
GO:0000978 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000980 IDA RNA polymerase II distal enhancer sequence-specific DNA binding
GO:0000981 IDA sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0001085 IPI RNA polymerase II transcription factor binding
GO:0001102 IPI RNA polymerase II activating transcription factor binding
GO:0001191 IDA RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription
GO:0001570 IMP vasculogenesis
GO:0001756 IMP somitogenesis
GO:0001839 IMP neural plate morphogenesis
GO:0001843 IMP neural tube closure
GO:0003007 IEA heart morphogenesis
GO:0003257 IMP positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation
GO:0003705 IEA RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0006357 IDA regulation of transcription from RNA polymerase II promoter
GO:0006366 IDA transcription from RNA polymerase II promoter
GO:0007341 IMP penetration of zona pellucida
GO:0007498 IMP mesoderm development
GO:0007509 IMP mesoderm migration involved in gastrulation
GO:0008284 IMP positive regulation of cell proliferation
GO:0009653 IMP anatomical structure morphogenesis
GO:0009952 IMP anterior/posterior pattern specification
GO:0014028 IMP notochord formation
GO:0022414 IMP reproductive process
GO:0023019 IDA signal transduction involved in regulation of gene expression
GO:0030509 IDA BMP signaling pathway
GO:0030903 IMP notochord development
GO:0036342 IGI post-anal tail morphogenesis
GO:0043565 IDA sequence-specific DNA binding
GO:0045944 IGI positive regulation of transcription from RNA polymerase II promoter
GO:0048706 IMP embryonic skeletal system development
GO:0055007 NAS cardiac muscle cell differentiation
GO:0060070 IDA canonical Wnt signaling pathway
GO:0060349 IGI bone morphogenesis
GO:0060395 IDA SMAD protein signal transduction
GO:0061371 IMP determination of heart left/right asymmetry

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000115394 tbx19-201 protein_coding Danio_rerio 0 375
ENSDART00000150167 tbx19-001 protein_coding Danio_rerio 0 375
ENST00000296946 T-001 protein_coding Homo_sapiens 0 1386
ENST00000366871 T-002 protein_coding Homo_sapiens 0 929
ENST00000366876 T-003 protein_coding Homo_sapiens 0 1312
ENST00000461348 T-004 protein_coding Homo_sapiens 0 928
ENST00000604110 RP11-293B7.1-001 processed_pseudogene Homo_sapiens 0 316

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