C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: cofilin 2, muscle
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000062929 Cfl2 10090 - 12:54858817-54862877 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000078124 Cfl2-201 54858817-54862877 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000078124
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000078124 6.952±2.73 6.896±1.61 36.358±3.93 9.549±3.08 7.514±5.21 6.419±2.06 21.573±7.76 7.991±2.69 5.610±2.20 13.062±2.15 97.738±9.37 4.410±1.64 13.756±4.07 7.105±1.44

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005RE CIL_0005RE_0003 CGP 12:54746349-54862877
CIL_0005RD CIL_0005RD_0003 CGP 12:54858817-55014348

Gene Ontology

GO IDEvidence TypeGO Description
GO:0003674 ND molecular_function
GO:0003779 IEA actin binding
GO:0005515 IEA protein binding
GO:0005615 IEA extracellular space
GO:0005634 IEA nucleus
GO:0007015 IMP actin filament organization
GO:0015629 IEA actin cytoskeleton
GO:0030042 IEA actin filament depolymerization
GO:0030836 IEA positive regulation of actin filament depolymerization
GO:0031674 IEA I band
GO:0045214 IMP sarcomere organization
GO:0046716 IMP muscle cell cellular homeostasis
GO:0061001 IMP regulation of dendritic spine morphogenesis
GO:0070062 IEA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000014106 cfl2 cofilin 2 (muscle) protein_coding Danio_rerio
ENSG00000165410 CFL2 cofilin 2 (muscle) protein_coding Homo_sapiens

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