C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: cofilin 2 (muscle)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000165410 CFL2 9606 - 14:34706769-34714823 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000298159 CFL2-001 34706769-34714690 protein_coding
  ENST00000341223 CFL2-002 34710387-34713828 protein_coding
  ENST00000422678 CFL2-003 34712037-34714577 nonsense_mediated_decay
  ENST00000554470 CFL2-004 34712008-34714823 nonsense_mediated_decay
  ENST00000555765 CFL2-005 34712852-34714555 protein_coding
  ENST00000556161 CFL2-006 34712858-34714236 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000298159ENST00000341223ENST00000422678ENST00000554470ENST00000555765ENST00000556161
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000298159 N/A 1.112±0.00 0.654±0.00 N/A N/A N/A N/A N/A N/A 0.620±0.00 N/A N/A N/A N/A
ENST00000341223 9.731±0.00 1.971±0.00 1.233±0.00 10.187±3.66 5.126±1.77 6.103±0.49 23.786±10.90 8.278±0.00 12.706±9.65 3.773±0.00 20.464±3.64 5.350±2.11 5.692±1.58 11.984±5.71
ENST00000422678 N/A N/A N/A 7.369±0.00 5.787±0.00 N/A 11.890±0.00 N/A N/A N/A 34.859±0.00 5.275±1.46 6.293±1.28 5.495±0.00
ENST00000554470 13.622±0.00 8.313±0.00 1.547±0.00 50.596±0.00 17.483±0.00 26.211±0.00 49.579±0.00 10.272±0.00 17.640±0.00 12.134±0.00 92.009±0.00 7.542±3.66 6.021±0.00 17.549±8.72
ENST00000555765 N/A N/A N/A 40.571±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000556161 N/A N/A 12.530±0.00 51.270±0.00 31.396±0.00 30.320±0.00 65.945±0.00 53.726±0.00 97.745±0.00 28.754±0.00 274.276±0.00 14.852±0.00 7.263±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005RE CIL_0005RE_0002 CGP 14:34561094-34714823
CIL_0005RD CIL_0005RD_0002 CGP 14:34706769-34875647

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003779 IEA actin binding
GO:0005515 IPI protein binding
GO:0005615 IDA extracellular space
GO:0005622 IEA intracellular
GO:0005634 IEA nucleus
GO:0007015 IEA actin filament organization
GO:0015629 IEA actin cytoskeleton
GO:0030042 IEA actin filament depolymerization
GO:0030836 IMP positive regulation of actin filament depolymerization
GO:0031674 IDA I band
GO:0045214 IEA sarcomere organization
GO:0046716 IEA muscle cell cellular homeostasis
GO:0061001 ISS regulation of dendritic spine morphogenesis
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000014106 cfl2 cofilin 2 (muscle) protein_coding Danio_rerio
ENSMUSG00000062929 Cfl2 cofilin 2, muscle protein_coding Mus_musculus

Loading