C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000073957 Sema3e-001 ENSMUSG00000063531 10090 + 5:14025317-14256689 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000073957
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000073957 0.174±0.14 0.082±0.01 0.371±0.02 1.365±1.05 0.174±0.06 0.448±0.21 0.035±0.02 0.492±0.23 0.017±0.01 9.304±0.71 0.050±0.02 0.558±0.34 2.147±0.94 0.058±0.03

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003CW CIL_0003CW_0002 CGP 5:14025276-14860184

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001569 IMP patterning of blood vessels
GO:0001953 IMP negative regulation of cell-matrix adhesion
GO:0002040 IMP sprouting angiogenesis
GO:0004872 IEA receptor activity
GO:0005515 IPI protein binding
GO:0005576 NAS extracellular region
GO:0007399 IEA nervous system development
GO:0008360 IMP regulation of cell shape
GO:0016020 IEA membrane
GO:0016525 IMP negative regulation of angiogenesis
GO:0030154 IEA cell differentiation
GO:0030215 IPI semaphorin receptor binding
GO:0050808 IMP synapse organization
GO:0071526 IMP semaphorin-plexin signaling pathway
GO:2000249 IMP regulation of actin cytoskeleton reorganization

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000307792 SEMA3E-001 protein_coding Homo_sapiens 0 2523
ENST00000427262 SEMA3E-002 protein_coding Homo_sapiens 0 2340
ENST00000442159 SEMA3E-004 protein_coding Homo_sapiens 0 592
ENST00000453333 SEMA3E-003 nonsense_mediated_decay Homo_sapiens 8e-22 108

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