C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: insulinoma-associated 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000068154 Insm1 10090 + 2:146221921-146225020 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000089257 Insm1-001 146221921-146225020 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000089257
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000089257 0.012±0.00 4.203±1.68 0.021±0.00 17.317±13.64 2.292±1.59 2.162±0.28 0.010±0.00 0.072±0.04 0.035±0.06 0.116±0.06 0.147±0.00 0.308±0.16 0.035±0.02 0.015±0.01

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003Q7 CIL_0003Q7_0002 CGP 2:145934784-146225020
CIL_0007R6 CIL_0007R6_0002 VISTA 2:146024701-146625932
CIL_0001TW CIL_0001TW_0002 CGP 2:146221921-146512026

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 ISS negative regulation of transcription from RNA polymerase II promoter
GO:0001047 ISS core promoter binding
GO:0001933 ISS negative regulation of protein phosphorylation
GO:0003309 IDA type B pancreatic cell differentiation
GO:0003310 IDA pancreatic A cell differentiation
GO:0003323 IMP type B pancreatic cell development
GO:0003358 IMP noradrenergic neuron development
GO:0003700 ISS sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005829 TAS cytosol
GO:0006351 IEA transcription, DNA-templated
GO:0007049 IEA cell cycle
GO:0008285 ISS negative regulation of cell proliferation
GO:0010468 IMP regulation of gene expression
GO:0017053 ISS transcriptional repressor complex
GO:0030154 IMP cell differentiation
GO:0030332 IEA cyclin binding
GO:0031018 IMP endocrine pancreas development
GO:0031490 ISS chromatin DNA binding
GO:0035270 IMP endocrine system development
GO:0042421 IMP norepinephrine biosynthetic process
GO:0042826 IEA histone deacetylase binding
GO:0043254 ISS regulation of protein complex assembly
GO:0045597 IMP positive regulation of cell differentiation
GO:0046872 IEA metal ion binding
GO:0060290 ISS transdifferentiation
GO:0061104 IMP adrenal chromaffin cell differentiation
GO:0061549 IMP sympathetic ganglion development
GO:0071158 ISS positive regulation of cell cycle arrest
GO:2000179 IMP positive regulation of neural precursor cell proliferation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000173404 INSM1 insulinoma-associated 1 protein_coding Homo_sapiens

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